Computational Toxicology [E-Book]: Volume II / edited by Brad Reisfeld, Arthur N. Mayeno.
Mayeno, Arthur N.
Reisfeld, Brad.
Totowa, NJ : Humana Press, 2013
XI, 648 p. 153 illus., 62 illus. in color. digital.
Methods in molecular biology, methods and protocols ; 930
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Table of Contents:
  • Methods for Building QSARs
  • Accessing and Using Chemical Databases
  • From QSAR to QSIIR: Searching for Enhanced Computational Toxicology Models
  • Mutagenicity, Carcinogenicity and Other Endpoints
  • Classification Models for Safe Drug Molecules
  • QSAR and Metabolic Assessment Tools in the Assessment of Genotoxicity
  • Gene Expression Networks
  • Construction of Cell Type-Specific Logic Models of Signaling Networks Using CellNetOptimizer
  • Regulatory Networks
  • Computational Reconstruction of Metabolic Networks from KEGG
  • Biomarkers
  • Biomarkers: Environmental Public Health Indicators
  • Modeling for Regulatory Purposes (Risk and Safety Assessment)
  • Developmental Toxicity Prediction
  • Predictive Computational Toxicology to Support Drug Safety Assessment
  • Developing a Practical Toxicogenomics Data Analysis System Utilizing Open-Source Software
  • Systems Toxicology from Genes to Organs
  • Agent Based Models of Cellular Systems
  • Linear Algebra
  • Ordinary Differential Equations
  • On the Development and Validation of QSAR Models
  • Principal Components Analysis
  • Partial Least Square Methods: Partial Least Squares Correlation and Partial Least Square Regression
  • Maximum Likelihood
  • Bayesian Inference..