Mechanism of Functional Expression of the Molecular Machines [E-Book] / by Masahiro Kinoshita.
This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor...
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Full text |
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| Personal Name(s): | Kinoshita, Masahiro, author |
| Imprint: |
Singapore :
Springer,
2016
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| Physical Description: |
X, 70 p. 30 illus., 24 illus. in color. online resource. |
| Note: |
englisch |
| ISBN: |
9789811014864 |
| DOI: |
10.1007/978-981-10-1486-4 |
| Series Title: |
SpringerBriefs in Molecular Science
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| Subject (LOC): |
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This brief discusses the mechanism of functional expression of a protein or protein complex utilizing the ATP hydrolysis cycle or proton-motive force from a unique point of view focused on the roles of water. A variety of processes are considered such as the unidirectional movement of a linear-motor protein along a filament, insertion of an unfolded protein into a chaperonin and release of the folded protein from it, transport of diverse substrates across the membrane by a transporter, and directed rotation of the central subunit within a rotatory motor protein complex. These topics are discussed in a unified manner within the same theoretical framework. The author argues that water plays imperative roles in the functional expression of these molecular machines. A pivotal factor is the entropic force or potential originating from the translational displacement of water molecules coexisting with the molecular machines in the entire system. |