Photodynamic medicine : from bench to clinic [E-Book] / [editors] Herwig Kostron, Tayyaba Hasan.
Kostron, Herwig, (editor)
Hasan, Tayyaba, (editor)
[Cambridge] : Royal Society of Chemistry, 2016
1 online resource.
Comprehensive series in photochemical & photobiological sciences ; 15
Full Text
Table of Contents:
  • The Journey of PDT Throughout History: PDT from Pharos to Present; 1.1. Introduction; 1.2. The PDT Tree; 1.2.1. The Tree Roots (Origins of PDT); 1.3. Development of PDT; 1.4. Development of PSs; 1.5. Light Sources; 1.6. Recent Trends in PDT Applications; 1.6.1. Therapeutic Combinations in Which PDT Is the Core Therapeutic Partner; PDT and Chemotherapy
  • PDT and Radiation Therapy.Radiation therapy or RT is a treatment modality that utilizes ionizing radiation in order to d... PDT and Immunotherapy.Any cancer treatment modality should not only destroy the tumor at its primary site, but also acti...; Angiogenesis Inhibitors.PDT may induce direct vascular damage and subsequently more extensive injury due to internalizat...; PDT and Antioxidants.The well-known mechanism of PDT action on tumorous and non-tumorous cells can be simplified by the ...
  • PDT and Receptor Inhibition.Cell growth is mediated through different receptors and downstream cell signaling cascades. ...1.6.2. Nanotechnology-Based PDT; Nanovehicles Acting Only As PS Carriers.Nanovesicles, namely liposomes, transferosomes, niosomes and others, are tiny ve...; 1.7. Other Significant Applications of PDT; References; Chapter 2
  • Photosensitisers for Photodynamic Therapy: State of the Art and Perspectives; 2.1. Introduction to Photosensitisation; 2.2. Clinical PSs; 2.2.1. PSs for Cancer Therapy; 2.2.2. PSs for Antimicrobial PDT
  • 2.2.3. PSs for Other Indications2.3. Preclinical PSs of Natural Origin; 2.3.1. Tetrapyrroles; 2.3.2. Flavins; 2.3.3. Phenalenones; 2.3.4. Perylenequinones; 2.3.5. Other Families; 2.4. Preclinical Synthetic PSs; 2.4.1. Porphyrinoids; 2.4.2. Non-Porphyrinoid PSs; 2.5. Activatable PSs; 2.5.1. Activation by Molecular Recognition; 2.5.2. Enzyme Activation; 2.5.3. pH-Sensitive PSs; 2.5.4. Small-Molecule Activation; 2.5.5. Photoactivatable PSs; 2.5.6. Polarity-Sensitive PSs; 2.5.7. Multi-Stimulus Responsive PSs; 2.6. Photoimmunoconjugates; 2.6.1. Bioconjugation Strategies; 2.6.2. Early Conjugates
  • 2.6.3. Recent Trends2.6.4. Fluorogenic and Chromogenic Theranostic PICs; 2.7. Genetically Encoded PSs; 2.7.1. GFP Homologues; 2.7.2. Flavin-Binding FPs; 2.8. Photosensitising Nanomaterials; 2.8.1. Nanomaterials as Novel Types of PSs; Carbon Nanostructures.The era of carbon nanostructures started in 1985 with the discovery of buckminsterfullerene (C60),...; Porous Silicon Nanoparticles.Among all of the metalloid materials that have been isolated as nanostructures, silicon nan...