Neuronal networks in brain function, CNS disorders, and therapeutics [E-Book] / edited by Carl L. Faingold, Hal Blumenfeld.
Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control...
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| Personal Name(s): | Faingold, Carl, editor |
| Blumenfeld, Hal, editor | |
| Imprint: |
London :
Academic Press,
2014
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| Physical Description: |
1 online resource (537 pages) : color illustrations |
| Note: |
englisch |
| ISBN: |
9780124158641 9780124158047 0124158048 0124158641 |
| Subject (LOC): |
| LEADER | 15407cam a2200565Ma 4500 | ||
|---|---|---|---|
| 001 | ocn867318756 | ||
| 003 | OCoLC | ||
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| 020 | |a 0124158048 | ||
| 035 | |a (Sirsi) a647051 | ||
| 041 | |a eng | ||
| 082 | 0 | 4 | |a 616.855 |
| 245 | 0 | 0 | |a Neuronal networks in brain function, CNS disorders, and therapeutics |h [E-Book] / |c edited by Carl L. Faingold, Hal Blumenfeld. |
| 264 | 1 | |a London : |b Academic Press, |c 2014 |e (ScienceDirect) |f ScienceDirectNeuroscience2014 | |
| 300 | |a 1 online resource (537 pages) : |b color illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 500 | |a englisch | ||
| 520 | |a Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understa. | ||
| 505 | 0 | |a 1. Introduction to Neuronal Networks of the Brain / Hal Blumenfeld -- Introduction -- "Silos" in CNS Network Research -- Types of Network Interactions -- Epilepsy as a Template for Network Studies -- Network Technical Approaches -- Computational Approaches to Neuronal Networks -- Network Exploration Process: An Overview -- Neuronal Network versus Neuroanatomy -- Emergent Properties of Neuronal Networks -- Mechanisms Responsible for Network Control -- Neuroplasticity -- Emergent Properties of Networks as Therapeutic Targets -- References -- 2.Network Models of Absence Seizures / Alain Destexhe -- Introduction -- Experimental Characterization of Generalized Spike and Wave Seizures -- Network Models of Spike-and-Wave Seizures -- Testing the Predictions of the Models -- Conclusions: A Corticothalamic Mechanism for Absence Seizures -- References -- Further Reading. | |
| 505 | 8 | |a 3. Functional Magnetic Resonance Imaging in Epilepsy: Methods and Applications Using Awake Animals / Jeffrey Tenney -- Introduction -- Setting Up and Imaging Awake Animals -- Spatial Resolution and Neuroanatomical Fidelity -- Data Analysis -- Awake Seizure Studies -- Summary -- References -- 4.Network Experimental Approaches: Inactivation, Microinjection, Neuronal Stimulation, and Recording / Carl L. Faingold -- Introduction -- Inactivation Techniques -- Neuronal Stimulation -- Neuronal Recording -- Conclusions -- References -- 5.Network Experimental Approaches: Ex Vivo Recording / Victor V. Uteshev -- Introduction -- Direct Synchronization via Chemical and Electrical Synapses in the Olfactory Bulb -- Inhibition of Asynchrony in Spontaneous Activity of Hypothalamic Histaminergic TM Neurons -- Stochastic Enhancement of Neuronal Excitability: Can a Single Ion Channel Excite the Entire Neuron? -- Conclusion -- References. | |
| 505 | 8 | |a 6.Network Imaging / Hal Blumenfeld -- Introduction -- The Relationship between Anatomical and Functional Connectivity -- Network Properties and Measures -- The Neuroenergetic Basis for Small-World Network Functions -- Methods for Extracting Network Activity -- Electrophysiological Activity is Related to Resting Functional Connectivity -- Oscillatory Networks Can Be Measured by EEG and MEG -- Networks in Cognition and Consciousness -- Network Disruptions in Disease -- Conclusion -- References -- 7.Network Control Mechanisms: Cellular Inputs, Neuroactive Substances, and Synaptic Changes / Carl L. Faingold -- Introduction -- Projection Neuron Inputs -- Multiple Inputs -- Electrophysiological Mechanisms -- Neuroactive Substances -- Cytokine Involvement in Network Control -- Synaptic Strength Changes, Synaptogenesis, and Neurogenesis -- Neurotropic Factors -- Axonal Sprouting -- Neurogenesis -- Conclusions -- References. | |
| 505 | 8 | |a 8. Volume Transmission and the Russian-Doll Organization of Brain Cell Networks: Aspects of Their Integrative Actions / K. Fuxe -- General Premises -- Introduction -- On the Structural Organization of the CNS -- The Dichotomy Distinction between Wiring and Volume Transmission -- Concluding Remarks -- General Conclusion -- References -- 9. Electrophysiological Mechanisms of Network Control: Bursting in the Brain -- From Cells to Networks / Peter L. Carlen -- Introduction -- Mechanisms Underlying the Single-Unit and Local Field Potential -- Measured Bursts -- Neuronal Bursting: Seizures -- Conclusion -- References -- 10.Network Control Mechanisms -- Cellular Milieu / Evgeny A. Sametsky -- Introduction -- Effects of the Extracellular Ionic Composition on Neuronal Network Activity -- Effects of Oxygen on Neuronal Activity -- Effects of Osmolarity on Neuronal Activity -- Effects of pH on Neuronal Activity -- Effects of Temperature on Neuronal Activity. | |
| 505 | 8 | |a Effects of Glial Cells on Neuronal Activity -- Extracellular Ions and Ex vivo Models of Seizure -- Evaluation of Distance and Time Dependence of Drug Diffusion in the Extracellular Space -- Conclusion -- References -- 11. Neuronal Network Mechanisms -- Sex and Development / Solomon L. Moshe -- Introduction -- Basal Ganglia -- Corticothalamic Network -- Conclusions -- References -- 12. Astrocytic Regulation of Synapses, Neuronal Networks, and Behavior / Tommaso Fellin -- Introduction -- Astrocytic-Neuronal Structural Association -- Gliotransmission: The Release of Chemical Transmitters by Astrocytes -- Complexity of Astrocyte-to-Neuron Communication -- Vesicular ATP Release from Astrocytes and Its Functional Consequences on Neuronal Function -- Gliotransmission Modulates Network Activity and Cortical Rhythms In vivo -- Astrocytes Regulate Sleep-Related Behaviors -- Astrocytic Neuromodulation Contributes to Feedback Control of Breathing. | |
| 505 | 8 | |a Concluding Remarks -- References -- 13. The Fear Memory Network / Glenn E. Schafe -- An Overview of Pavlovian Fear Conditioning -- The Amygdala and Fear Conditioning -- Synaptic Plasticity in the Amygdala and Fear Conditioning -- Distributed versus Local Plasticity in the Amygdala -- Plasticity beyond the Amygdala -- Contextual Fear Conditioning -- Turning Fear Off: Fear Extinction -- Fear Learning in Humans and Its Relevance to Anxiety Disorders -- Conclusions -- References -- 14. Orchestration of the Circadian Clock Network by the Suprachiasmatic Nucleus / Stacey L. Krager -- Introduction -- The Cellular Basis of Circadian Rhythmicity -- SCN as the Master Clock -- Input to the SCN -- Gating of the SCN -- SCN Output -- SCN Control of Locomotor Activity -- SCN Control of the Adrenal Gland -- SCN Control of the Female Reproductive Cycle -- SCN Control of the Pineal Gland -- SCN Control of Metabolism -- Circadian Rhythms in Health and Disease. | |
| 505 | 8 | |a Conclusions -- References -- 15.mTOR Signaling in Cortical Network Development / Angelique Bordey -- Introduction -- Background -- Methods: In utero Electroporation -- Current Research -- Unanswered Questions and Future Research -- Conclusion -- References -- 16.Network Control Mechanisms -- Synaptogenesis and Epilepsy Development / F. Edward Dudek -- References -- 17. The Brain and Spinal Cord Networks Controlling Locomotion / Urszula Slawinska -- Descending Control of Locomotion -- The Locomotor Areas of the Brain for Selection of Locomotion -- CPG Interneurons -- Interneurons Identified on the Basis of Progenitor Domain -- Sensory Control of Locomotion -- Clinical Applications -- Concluding Remarks -- References -- 18. The Brainstem Respiratory Network / Kendall F. Morris -- Functions of the Brainstem Respiratory Network -- Anatomy of the Respiratory System -- Dorsal Respiratory Group -- Ventral Respiratory Column. | |
| 505 | 8 | |a Interactions with Other Networks and Reconfiguration for Airway Protection -- Summary -- References -- 19. Visual Network / Moran Furman -- Introduction -- Retinal Circuits for Initial Visual Processing -- Subcortical Visual Pathways -- The Colliculo-Pulvinar-Cortical Pathway -- The Primary Visual Cortex -- Ventral and Dorsal Cortical Pathways for Visual Processing -- The Neural Basis of Conscious Visual Experience -- Loss of Visual Awareness following Localized Lesions in the Vision Network -- Neural Correlates of Perceived Stimulus Properties -- Conceptual Model: Brain Networks for Visual Awareness -- References -- 20. Auditory Neuronal Networks and Chronic Tinnitus / Carol A. Bauer -- Tinnitus Phenomenology and Epidemiology -- Processing Acoustic Information: The Auditory Pathway -- De-afferentation and Homeostatic Compensation -- Animal Models -- Compensation and Overcompensation in the Brainstem -- Loss of Inhibition -- Auditory Cortex and Amygdala. | |
| 505 | 8 | |a Nonauditory Brain Areas -- A Cellular Component of Tinnitus -- Conclusions -- References -- 21. Consciousness and Subcortical Arousal Systems / Hal Blumenfeld -- Introduction -- Acetylcholine -- Norepinephrine -- Histamine -- Serotonin -- Orexin -- Glutamate -- Dopamine -- Conclusions -- List of Abbreviations -- References -- 22.Networks of Normal and Disordered Sleep / Patrice Fort -- Introduction -- Mechanisms Involved in Waking (Figure 22.1) -- Mechanisms Involved in NREM (SWS) Induction and Maintenance (Figure 22.2) -- Mechanisms Controlling the Activity of NREM (SWS) Sleep-Inducing Neurons -- Overview of the Neuronal Network Responsible for SWS (NREM) Sleep (Figure 22.2) -- Mechanisms Involved in Paradoxical (REM) Sleep Genesis (Figure 22.3) -- Paradoxical (REM) Sleep-Generating Neurons: The Switch from Acetylcholine to Glutamate -- Mechanisms Responsible for SLD PS-on Neuron Activation during PS. | |
| 505 | 8 | |a Neurons Inhibiting the GABAergic and Monoaminergic PS-off Neurons at the Onset of and during PS -- Role of the MCH and GABAergic Neurons of the Lateral Hypothalamic Area in PS Control -- Conclusion -- References -- 23.Networks for the Modulation of Acute and Chronic Pain / Marshall Devor -- Introduction -- Pain-Processing Pathways -- Processing Changes in Chronic Pain -- The Mesopontine Tegmental Anesthesia Area (MPTA) -- Discovery of the MPTA -- MPTA Connectivity: Interrelationship with the Pain Control Network -- Network Interactions and Therapeutic Implications -- Summary -- References -- 24.Networks in Mood and Anxiety Disorders / Hamada Hamid -- Amygdala -- Hippocampus -- Prefrontal Cortex -- Basal Ganglia -- Conclusion -- References -- 25. Neuronal Networks and Therapeutics in Neurodegenerative Disorders / Duarte G. Machado -- Introduction -- Basal Ganglia -- Parkinson's Disease -- Essential Tremor -- Primary Torsion Dystonia. | |
| 505 | 8 | |a Tourette's Syndrome -- Huntington's Disease -- Alzheimer's Disease -- Conclusion -- References -- 26. Neuronal Networks in Epilepsy: Comparative Audiogenic Seizure Networks / Prosper N'Gouemo -- Introduction -- Developmental Epilepsy Networks -- Networks for Absence Epilepsy Models -- Networks for Epilepsy Kindling Models -- Status Epilepticus Networks -- Networks for Generalized Human Epilepsy -- Forms of AGS -- Genetic Forms of AGS Susceptibility -- Induced Forms of AGS -- Thyroid-Deficient Form of AGS Susceptibility -- Ischemia-Induced Form of AGS Susceptibility -- Alcohol Withdrawal (ETX)-Induced AGS Susceptibility -- AGS Severity -- Neuronal Networks in AGS -- AGS Neuronal Network Studies -- Blockade Studies of the IC in Induced AGS Models -- Blockade of the IC in the Ischemia Model -- The DLSC in AGS Networks -- Role of the PAG in AGS Networks -- The PRF in AGS Networks -- Role of the Substantia Nigra Reticulata in AGS Networks. | |
| 505 | 8 | |a Forebrain Structures in AGS -- Hierarchical Organization of the AGS Network -- Conclusions -- References -- 27. Physiological and Pathophysiological Expansion of Neuronal Networks / Carl L. Faingold -- Neuronal Network Expansion Mechanisms -- Conclusions -- References -- 28. Neuronal Network Plasticity and Network Interactions are Critically Dependent on Conditional Multireceptive (CMR) Brain Regions / James D. Stittsworth, Jr. -- Introduction -- Common Characteristics of CMR Neurons -- Specific Characteristics and Comparison of Neurons in Different CMR Regions -- Interaction of CMR Regions -- Conclusions -- References -- 29. Neuronal Network Interactions in the Startle Reflex, Learning Mechanisms, and CNS Disorders, Including Sudden Unexpected Death in Epilepsy / Srinivasan Tupal -- Introduction -- Dual Network Interactions -- Multinetwork Interactions -- Conclusions -- References -- 30. Emergent Properties of Neuronal Networks / Carl L. Faingold. | |
| 505 | 8 | |a Emergent Properties of Neuronal Networks -- Types of Emergent Properties -- Levels of Emergent Properties -- Respiratory Networks of the Brainstem -- Motor Control -- Sensory Processing -- Normal Brain State Transitions -- Cognition and Memory -- Neurological Disorders -- Epilepsy -- Psychiatric Disorders -- Conclusions -- References -- 31. Neuronal Network Involvement in Stimulation Therapies for CNS Disorders / Hua-Jun Feng -- Introduction -- Noninvasive Stimulation Modalities -- Invasive Stimulation Modalities -- General Neuronal Network Mechanisms of Stimulation Therapies -- Conclusion -- References -- 32. Neuronal Network Effects of Drug Therapies for CNS Disorders / Carl L. Faingold -- Introduction -- The Brainstem Reticular Formation Arousal Network -- The Centrencephalic Theory of Generalized Epilepsy -- CNS Drugs Dosage -- Mesoscopic Networks and CNS Drugs -- The Brain You Anesthetize May Be Your Own -- Drug Effects on Network Emergent Properties. | |
| 505 | 8 | |a Selective Effects of CNS Drugs: Therapeutic Doses -- Drug Effects on Rhythmic Oscillations of the Brain -- Pharmacological Magnetic Resonance Imaging Studies -- Drug Effects on Intact Neuronal Networks -- Stimulant Drug Effects on Neuronal Network Neurons -- Stimulant Drug Effects and Cognition -- Depressant and Anesthetic Drug Effects on Neuronal Networks -- Effects of Ethanol on Neurons in Neuronal Networks -- Ethanol and Emergent Properties of Neurons -- Effects of Anticonvulsant Drugs on Intact Neuronal Networks for Seizures -- Anticonvulsant Actions on IC Neurons -- Anticonvulsant Actions on PAG and BRF Neurons -- Anticonvulsant Actions on the Substantia Nigra Reticulata (SNr) -- Emergent Properties: Differences between In vivo and In vitro Studies -- Understanding Emergent Properties as Critical Drug Targets -- "Anticonvulsant" Drug Effects on Networks for Multiple CNS Disorders -- CNS Drugs and Long-Lasting Network Changes -- Conclusion. | |
| 650 | 0 | |a Neural networks (Neurobiology) | |
| 650 | 0 | |a Neuroanatomy. | |
| 650 | 0 | |a Nervous system |x Diseases. | |
| 650 | 2 | |a Nerve Net |x physiology. | |
| 650 | 2 | |a Neurons |x physiology. | |
| 650 | 2 | |a Neuroanatomy. | |
| 650 | 2 | |a Central Nervous System Diseases |x therapy. | |
| 700 | 1 | |a Faingold, Carl, |e editor | |
| 700 | 1 | |a Blumenfeld, Hal, |e editor | |
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