Stem Cell-Derived Models in Toxicology [E-Book] / edited by Mike Clements, Liz Roquemore.
Clements, Mike, (editor)
Roquemore, Liz, (editor)
New York, NY : Humana Press, 2017
XII, 341 p. 124 illus., 108 illus. in color. online resource.
englisch
9781493966615
10.1007/978-1-4939-6661-5
Methods in pharmacology and toxicology
Full Text
Table of Contents:
  • Stem CellDerived Models for Safety and Toxicity Assessments: Present and Future Studies in the Proclinical Space
  • Human Pluripotent Stem Cell Test for Assessing the Potential Teratogen Risk
  • Cardiac Action Potential Measurement in Human Embryonic Stem Cell Cardiomyocytes for Cardiac Safety Studies Using Manual Patch-Clamp Electrophysiology
  • Automated Patch Clamp Recordings of Human Stem Cell-Derived Cardiomyocytes
  • The CiPA Microelectrode Array Assay with hSC-Derived Cardiomyocytes: Current Protocol, Future Potential
  • Optogenetic Approach to Cardiotoxicity Screening: Simultaneous Voltage and Calcium Imaging Under Paced Conditions
  • HTS Compatible Voltage- and Ca2+-Sensitive Dye Recordings from hiPSC-Derived Cardiomyocytes Using the Hamamatsu FDSS Systems
  • Kinetic Image Cytometry for Predicting Arrhythmias Using Human Stem Cell-Derived Cardiomyocytes
  • Decoding Ca2+ Signals as a Non-Electrophysiological Method for Assessing Drug Toxicity in Stem-Cell Derived Cardiomyocytes
  • Combined Impedance and Extracellular Field Potential Recordings from Human Stem Cell-Derived Cardiomyocytes
  • Edge Detection for Contractility Measurements with Cardiac Spheroids
  • Contractile Force Readout of hESC-Cardiomyocytes
  • In Vitro Cardiotoxicity Investigation Using High Content Analysis and Human Stem Cell-Derived Models
  • Structural Toxicity: Hypertrophy Models of Human Pluripotent Stem Cell-Derived Cardiomyocytes
  • Addressing Functional Neurotoxicity Using the Microelectrode Array (MEA)
  • Micropatterned Co-Cultures of Induced Pluripotent Stem Cell-Derived Hepatocytes and Stromal Cells for Drug Toxicity Studies.