Smart materials for tissue engineering [E-Book] / editor: Qun Wang.
Wang, Qun, (editor)
[Cambridge] : Royal Society of Chemistry, [2017]
1 online resource.
englisch
9781782626756
1782626751
Smart materials series ; 24
Full Text
Table of Contents:
  • Cover; Smart Materials for Tissue Engineering: Fundamental Principles; Foreword; Preface; Contents; Chapter 1
  • Smart Design of Materials for Tissue Engineering; 1.1 Introduction; 1.2 Mechanism Underlying Interaction of Cells with the Extracellular Matrix; 1.2.1 Direct Physical Signal Transmission Pathway; 1.2.2 Indirect Mechanochemical Signal Transduction Pathway; 1.2.3 Control of Cell Differentiation, Proliferation, and Migration by Defining the Dynamics of the Cell Adhesion Complex and Act...; 1.2.3.1 Stem Cell Differentiation; 1.2.3.2 Cell Proliferation; 1.2.3.3 Cell Migration
  • 1.3 Determinants of Cell Fate in the Extracellular Matrix1.3.1 Composition of Cell Adhesion Proteins; 1.3.2 ECM Topography; 1.3.3 ECM Stiffness; 1.4 Spatial and Temporal Scales in Cell and Material Interactions; 1.4.1 Molecular Level: Integrin; 1.4.2 Molecular Assembly Level; 1.4.2.1 Integrin Cluster; 1.4.2.2 Actin Cytoskeleton; 1.4.3 Single-Cell Level; 1.4.4 Multiple-Cell Level; 1.4.5 Integration of Multiple Spatiotemporal Effects; 1.5 Smart Design of Materials to Control the Dynamic State of Tissues; 1.6 Future Challenges; Acknowledgements; References
  • 2.4.5 Multi-Modal Delivery2.4.6 Scaffolds for Bone Tumor Destruction; 2.5 Concluding Remarks and Perspectives; References; Chapter 3
  • Protein-Based Stimuli Responsive Materials for Tissue Engineering; 3.1 Stimuli Responsiveness; 3.2 Types of Stimuli Responsiveness; 3.2.1 Temperature Responsiveness; 3.2.2 Electrical Responsiveness; 3.2.3 Light Responsiveness; 3.2.4 pH Responsive; 3.2.5 Redox Responsiveness; 3.2.6 Ion-Responsive Polymers; 3.2.7 Glucose Responsiveness; 3.2.8 Enzyme-Responsive Polymers; 3.3 Types of Polymeric Stimuli-Responsive Structures; 3.3.1 Hydrogels; 3.3.2 Micelles
  • 3.3.3 Dendrimers3.3.4 Nanoparticles; 3.4 Protein-Based Responsive Systems; 3.5 Application in Tissue Engineering; 3.6 Conclusions and Future Perspectives; Acknowledgements; References; Chapter 4
  • Stimuli-Responsive Hydrogels for Tissue Engineering; 4.1 Introduction; 4.2 The Properties of Hydrogels for Tissue Engineering; 4.2.1 Mechanical Properties of Hydrogels; 4.2.2 Surface Chemistry of Hydrogels; 4.2.3 Biocompatibility and Biodegradability of Hydrogels; 4.2.4 Electrical Properties of Hydrogels; 4.3 Stimuli-Responsive Hydrogels; 4.3.1 Natural-Based Smart Hydrogels; 4.3.1.1 Chitosan
  • Chapter 2
  • Smart Surfaces Chemistry and Coating Materials for Tissue Engineering2.1 Introduction; 2.1.1 Tissue Engineering and Scaffolds; 2.1.2 Cell-EMC Interaction via Integrin and Surface Topography; 2.2 RGD Nanospacing; 2.2.1 Nanospacing in 2-D Substrates with Different Stiffness; 2.2.2 3-D Substrates; 2.3 Surface Topography-Mediated Stem Cell Fate; 2.4 Scaffold-Mediated Gene Delivery by Biomimetic Coating; 2.4.1 Gene-Transfer; 2.4.2 DNA/CP Complex as a Drug-Delivery System by Biomimetic Coating; 2.4.3 Polyplexes as Drug-Delivery Systems; 2.4.4 Targeting the Nucleus