Structure and Function of GPCRs [E-Book] / edited by Guillaume Lebon.
This book introduces readers to the latest advances in G protein-coupled receptor (GPCR) biology. It reviews our current understanding of the structural basis of ligand binding and allosteric mechanisms, following a decade of technological breakthroughs. Several examples of structure-based drug disc...
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Full text |
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Personal Name(s): | Lebon, Guillaume, editor |
Edition: |
1st edition 2019. |
Imprint: |
Cham :
Springer,
2019
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Physical Description: |
XIV, 289 pages 71 illustrations, 52 illustrations in color (online resource) |
Note: |
englisch |
ISBN: |
9783030245917 |
DOI: |
10.1007/978-3-030-24591-7 |
Series Title: |
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Topics in Medicinal Chemistry ;
30 |
Subject (LOC): |
- Structures of Non-rhodopsin GPCRs Elucidated Through X-Ray Crystallography
- NMR Spectroscopy for the Characterization of GPCR Energy Landscapes
- Structure and Activation Mechanism of GPCRs
- Structure-Based Discovery of GPCR Ligands from Crystal Structures and Homology Models
- Integration on Ligand and Structure Based Approaches in GPCRs
- Biased Agonist Pharmacochaperones: Small Molecules in the Toolbox for Selectively Modulating GPCR Activity
- Endosomal PTH Receptor Signaling Through cAMP and Its Consequence for Human Medicine
- Structure and Function Studies of GPCRs by Site-Specific Incorporation of Unnatural Amino Acids
- Fluorescent-Based Strategies to Investigate G Protein-Coupled Receptors: Evolution of the Techniques to a Better Understanding
- Modulation of Metabotropic Glutamate Receptors by Orthosteric, Allosteric, and Light-Operated Ligands. .