The micronucleus assay in toxicology [E-Book] / editors: Siegfried Knasmüller, Michael Fenech.
Fenech, Michael, (editor)
Knasmüller, Siegfried, (editor)
Cambridge : Royal Society of Chemistry, 2019
1 online resource (400 pages)
Issues in toxicology ; 39
Full Text
Table of Contents:
  • A Short Personal History of Micronuclei
  • Mechanisms by Which Genotoxins Cause Micronuclei and Other Nuclear Anomalies
  • The Fate of Micronuclei and Micronucleated Cells
  • Micronuclei and Their Association with Infertility, Pregnancy Complications, Developmental Defects, Anaemias, Inflammation, Diabetes, Chronic Kidney Disease, Obesity, Cardiovascular Disease, Neurodegenerative Diseases and Cancer
  • The Cytokinesis-block Micronucleus Cytome Assay in Human Lymphocytes
  • Micronucleus Cytome Assay with Buccal Cells
  • Experiments with Micronucleus Assays Using Nasal, Urothelial and Cervical Human Cells
  • Micronuclei in the Bone Marrow Cells of Rodents
  • The In Vitro Micronucleus Assay with Rodent Hepatocytes
  • Micronucleus Assays with Human Lymphocytes for in Vitro Genetic Toxicology Testing
  • The Micronucleus (MN) Assay Using Human-derived Cells
  • Micronucleus Experiments with Non-human Mammalian Cells
  • Micronucleus Experiments with Fish Cell Lines
  • The Piscine Erythrocyte Micronucleus Cytome Assay
  • Micronucleus Experiments with Reptiles
  • Micronucleus Assays in Amphibians
  • Micronucleus Experiments with Bivalve Molluscs
  • Micronucleus Assays with Meiotic Pollen Tetrad Cells of Tradescantia and with Mitotic Root Tip Cells of Allium cepa and Vicia faba
  • Automated Identification and Scoring of Micronuclei
  • Regulatory Aspects and Guidelines for the use of Micronucleus Assays in Mammalian and Human Cells
  • Micronucleus Assay: Epidemiological and Statistical Issues
  • Effects of Tobacco Smoking on Micronucleus Frequency
  • Khat, Betel, Coca and Tobacco Chewing: Genotoxic Effects in Micronucleus Assays
  • Electromagnetic Fields and Micronuclei
  • Use of the Micronucleus Assay in Occupational Studies Involving Exposure to Genotoxic Chemicals – an Overview
  • Ionising Radiation Exposure Biodosimetry Using the Lymphocyte Cytokinesis-block Micronucleus Cytome Assay
  • Heavy Metals – Lead, Mercury and Cadmium and Their Impact on DNA Damage Measured by the Micronucleus Assay
  • Heavy Metals II (Arsenic, Chromium, Nickel, Vanadium) and Micronuclei
  • Effect of In Vivo Formaldehyde Exposure on DNA Damage Measured by the Micronucleus Assay in Lymphocytes, Buccal, and Nasal Cells
  • Pesticide Exposure and Its Effects on Micronucleus Frequency
  • Petroleum, Its Derivatives and Micronuclei
  • Butadiene and Its Effects on Micronucleus Frequency
  • The Effect of Dust, Asbestos and Other Fibers on DNA Damage Measured Using the Micronucleus Assay
  • Use of Micronucleus Assays to Measure DNA Damage Caused by Coal Dust and Ash
  • The Micronucleus Assay as a Cytogenetic Biomarker of Ethylene Oxide Exposure
  • Use of Micronucleus Assays to Measure DNA Damage Caused by Cytostatic/Antineoplastic Drugs
  • Micronucleus Assay for Assessing Chromosomal Damage in Medical Workers Exposed to Anaesthetic Gases
  • Micronucleus Induction by Exposure to Vinyl Chloride