Type 2 Diabetes [E-Book] : Methods and Protocols / edited by Claire J. Stocker.
Stocker, Claire J., (editor)
2nd edition 2020.
New York, NY : Humana Press, 2020
X, 300 pages 50 illustrations, 32 illustrations in color (online resource)
Methods in Molecular Biology ; 2076
Full Text
Table of Contents:
  • Sixty Years of Drug Discovery for Type 2 Diabetes: Where Are We Now?
  • Practical Considerations for In Vivo Studies
  • Nutritional Models of Type 2 Diabetes Mellitus
  • Cheminformatics in the Identification of Drug Classes for the Treatment of Type 2 Diabetes
  • Whole Exome Sequencing (WES) for Illumina HISeq using Solution-Based Capture
  • Gene Expression Mining in Type 2 Diabetes Research
  • Pathways Enrichment Analysis of Gene Expression Data in Type 2 Diabetes
  • Diagnostic Genetic Testing for Monogenic Diabetes and Congenital Hyperinsulinemia
  • The Isolation and Purification of Rodent Pancreatic Islets of Langerhans
  • Characterization of Islet Leukocyte Populations in Human and Murine Islets by Flow Cytometry
  • Analysis of Histone Modifications in Rodent Pancreatic Islets by Native Chromatin Immunoprecipitation
  • Quantification of Pancreatic Islets: Using Image Analysis Tools
  • The Measurement of Calcium Signaling In Beta Cell Lines using Epifluorescence and Confocal Microscopy
  • Nitric Oxide and Redox State Measurements in Pancreatic Beta Cells
  • Primary Adipocytes as a Model for Insulin Sensitivity
  • Assessing Islet Transplantation Outcome in Mice
  • The Measurement of Insulin Secretion using Pancreas Perfusion in the Rodent.