Targeting Enzymes for Pharmaceutical Development [E-Book] : Methods and Protocols / edited by Nikolaos E. Labrou.
This volume explores detailed methods and experimental protocols evaluating the effect of a compound or a mixture of compounds on the action of enzymes that are significant targets in pharmaceuticals. Consisting of three sections, the book delves into recent biocomputing and bioinformatics protocols...
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Full text |
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Personal Name(s): | Labrou, Nikolaos E., editor |
Edition: |
1st edition 2020. |
Imprint: |
New York, NY :
Human Press,
2020
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Physical Description: |
XI, 290 pages 113 illustrations, 71 illustrations in color (online resource) |
Note: |
englisch |
ISBN: |
9781071601631 |
DOI: |
10.1007/978-1-0716-0163-1 |
Series Title: |
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Methods in Molecular Biology ;
2089 |
Subject (ZB): | |
Subject (LOC): | |
Classification: |
- In Silico Laboratory: Tools for Similarity-Based Drug Discovery
- The In Silico Fischer Lock-and-Key Model: The Combined Use of Molecular Descriptors and Docking Poses for the Repurposing of Old Drugs
- Determination of Half-Maximal Inhibitory Concentration of an Enzyme Inhibitor
- Applications of Differential Scanning Fluorometry and Related Technologies in Characterization of Protein-Ligand Interactions
- High-Throughput Differential Scanning Fluorimetry of GFP-Tagged Proteins
- Enzyme-Ligand Interaction Monitored by Synchrotron Radiation Circular Dichroism
- Measuring Small Molecule Binding to Escherichia coli AcrB by Surface Plasmon Resonance
- Systematic Screening of Viral Entry Inhibitors Using Surface Plasmon Resonance
- Screening of Beta-Secretase Inhibitors by Capillary Electrophoresis-Mass Spectrometry
- Electrophoretic Mobility Shift Assays with GFP-Tagged Proteins (GFP-EMSA)
- On-Line Enantioselective Capillary Electrophoretic Method for Screening Cytochrome P450 3A4 Inhibitors
- Enzymatic Bioautographic Methods
- High-Throughput Assessment of Metabolism-Induced Toxicity of Compounds on a 384-Pillar Plate
- Droplet-Based Microfluidics Methods for Detecting Enzyme Inhibitors
- Ligand Fishing: An Approach for the Discovery Inhibitors from Complex Biological Mixtures
- HMG-CoA Reductase as Target for Drug Development
- Lipoxygenases as Targets for Drug Development
- Cholinesterase as a Target for Drug Development in Alzheimer's Disease.