HCV: The Journey from Discovery to a Cure [E-Book] : Volume I / edited by Michael J. Sofia.
Sofia, Michael J, (editor)
1st edition 2019.
Cham : Springer, 2019
VIII, 463 pages 1 illustrations (online resource)
englisch
9783030282073
10.1007/978-3-030-28207-3
Topics in Medicinal Chemistry ; 31
Full Text
Table of Contents:
  • Identification of the virus, the medical need and clearing the blood supply
  • Mapping the HCV genome
  • The molecular virology of HCV
  • The development of the HCV replicon system
  • The Evolution of IFN therapy for HCV
  • Evolution of HCV NS5B Non-Nucleoside Inhibitors
  • Evolution of HCV NS5B Nucleoside & Nucleotide Inhibitors
  • Discovery and Development of Sofosbuvir
  • Discovery of Beclabuvir
  • Discovery of Dasabuvir
  • Evolution of HCV NS3/4 protease inhibitors
  • Discovery and Development of Telaprevir
  • Discovery and Development of Boceprevir
  • Discovery and Development of Asunaprevir.-Discovery and Development of Grazoprevir
  • Discovery and Development of Simeprevir
  • Discovery and Development of Paritaprevir & Glecaprevir.