Artificial Assemblies with Cooperative DNA Recognition [E-Book] / by Zutao YU.
This book presents three types of synthetically cooperative DNA recognizing assemblies, in order to advance the development of programmable DNA-binding pyrrole-imidazole polyamides (PIPs). PIPs represent the best-characterized class of small molecule DNA binders that can be modified to bind with any...
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Full text |
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Personal Name(s): | YU, Zutao, author |
Edition: |
1st edition 2020. |
Imprint: |
Singapore :
Springer,
2020
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Physical Description: |
XV, 136 pages 136 illustrations, 119 illustrations in color (online resource) |
Note: |
englisch |
ISBN: |
9789811544231 |
DOI: |
10.1007/978-981-15-4423-1 |
Series Title: |
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Springer Theses, Recognizing Outstanding Ph.D. Research
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Subject (LOC): |
- 1. Synthetic transcription factors (Syn-TFs): design, progress and perspectives
- 2. Pip-HoGu, an artificial assembly with cooperative DNA recognition capable of mimicking transcription factor pairs
- 3. Orthogonal γPNA dimerization domains empower DNA binders with cooperativity and versatility mimicking that of the transcription factor pairs
- 4. Advanced DNA binding system mimicking the cooperative function of transcription factor pairs precisely recruits the epigenetic modifiers to the DNA repeat binding sites.