Gapmers [E-Book] : Methods and Protocols / edited by Toshifumi Yokota, Rika Maruyama.
This volume presents a comprehensive collection of detailed state-of-the-art protocols for gapmer-mediated RNA knockdown from leaders in the field. Chapters detail a historical and contemporary perspective of RNase H-inducing antisense oligonucleotides called gapmers and gapmer-mediated RNA knockdow...
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| Personal Name(s): | Maruyama, Rika, editor |
| Yokota, Toshifumi, editor | |
| Edition: |
1st edition 2020. |
| Imprint: |
New York, NY :
Humana Press,
2020
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| Physical Description: |
XI, 247 pages 39 illustrations, 29 illustrations in color (online resource) |
| Note: |
englisch |
| ISBN: |
9781071607718 |
| DOI: |
10.1007/978-1-0716-0771-8 |
| Series Title: |
Methods in Molecular Biology ;
2176 |
| Subject (ZB): | |
| Subject (LOC): | |
| Classification: |
- Invention and Early History
- Development and Clinical Applications of Antisense Oligonucleotide Gapmers
- Knocking Down Long Non-coding RNAs using Antisense Oligonucleotide Gapmers
- Development of Antisense Oligonucleotide Gapmers for the Treatment of Huntington's Disease
- Development of Antisense Oligonucleotide Gapmers for the Treatment of Dyslipidemia and Lipodystrophy
- Inotersen for the Treatment of Hereditary Transthyretin Amyloidosis
- Degradation of Toxic RNA in Myotonic Dystrophy Using Gapmer Antisense Oligonucleotides
- DNA/RNA Heteroduplex Oligonucleotide for Highly Efficient Gene Silencing
- Tips for Successful lncRNA Knockdown using Gapmers
- Calcium-Mediated In Vitro Transfection Technique of Oligonucleotides with Broad Chemical Modification Compatibility
- Evaluating the Knockdown Activity of MALAT1 ENA Gapmers in vitro
- Albumin-binding Fatty Acid-modified Gapmer Antisense Oligonucleotides for Modulation of Pharmacokinetics
- The use of Gapmers for in vivo Suppression of Hepatic mRNA Targets
- Development of LNA Gapmer Oligonucleotide-Based Therapy for ALS/ FTD Caused by the C9orf72 Repeat Expansion
- Targeted Gene Silencing in Malignant Hematolymphoid Cells using GapmeR
- Gapmer Antisense Oligonucleotides to Selectively Suppress the Mutant allele in COL6A Genes in Sominant Ullrich Congenital Muscular Dystrophy
- Detection of Locked Nucleic Acid Gapmers from Mouse Samples using ELISA.