Sequence-Specific DNA Binders for the Therapy of Mitochondrial Diseases [E-Book] / by Takuya Hidaka.
This book describes the author's work on the development of sequence-specific DNA binders for the therapy of mitochondrial diseases. In the first chapter, the author provides a detailed background of pyrrole-imidazole polyamides (PIPs) and mitochondrial disease research followed by chapters pre...
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Full text |
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Personal Name(s): | Hidaka, Takuya, author |
Edition: |
1st edition 2022. |
Imprint: |
Singapore :
Springer,
2022
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Physical Description: |
XIII, 94 pages 50 illustrations, 47 illustrations in color (online resource) |
Note: |
englisch |
ISBN: |
9789811684364 |
DOI: |
10.1007/978-981-16-8436-4 |
Series Title: |
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Springer Theses, Recognizing Outstanding Ph.D. Research
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Subject (LOC): |
- General Introduction
- Creation of Synthetic Ligand for Mitochondrial DNA sequence Recognition and Promoter-Specific Transcription Suppression
- Allele-Specific Replication Inhibition of Mitochondrial DNA by MITO-PIP Conjugated with Alkylation Reagent
- Enhanced Nuclear Accumulation of Pyrrole-Imidazole Polyamides by Incorporation of the Tri-arginine Vector.