Recent Advances in the Treatment of Neurodegenerative Disorders [E-Book]
Researchers have tried various effective treatments that prevent the progressive neurodegeneration of neurons within the brain. Parkinson's disease (PD), Alzheimer's disease (AD), and Multiple sclerosis (MS) are some of the most common neurodegenerative diseases (NDDs). Recent Advances in...
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Full text |
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| Personal Name(s): | Rai, Sachchida Nand, editor |
| Imprint: |
UAE :
Bentham Science Publishers,
2021
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| Physical Description: |
1 online resource (232 pages) |
| Note: |
englisch |
| ISBN: |
9781681087726 |
- Cover
- Title
- Copyright
- End User License Agreement
- Contents
- Foreword
- Preface
- Acknowledgements
- List of Contributors
- An Introduction to Neurodegenerative Diseases and its Treatment
- Payal Singh1 and Sachchida Nand Rai2,*
- INTRODUCTION
- AYURVEDA IN NEURODEGENERATIVE DISEASES (NDS)
- VITAMINS IN NEURODEGENERATIVE DISEASES (NDS)
- GUT-BRAIN AXIS AND ASSOCIATED PRO AND PRE-BIOTICS THERAPY FOR NDS
- NANOPARTICLES AND NANOFORMULATION BASED THERAPY FOR DIFFERENT NDS
- CONCLUSION
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
- Recent Advancement in the Treatment of Neurodegenerative Diseases by Ayurveda
- Mridula Chaturvedi and Abhishek Kumar Chaturvedi*
- INTRODUCTION
- OVERVIEW OF NEURODEGENERATIVE DISEASES (NDDS)
- The Preamble of Common Neurodegenerative Diseases
- Alzheimer's Disease (AD)
- Parkinson's Disease (PD)
- Huntington's Disease (HD)
- Pathogenesis of Neurodegenerative Diseases
- Pathway of Development of Neurodegenerative Diseases
- Common Signs &
- Symptoms of Neurodegenerative Diseases
- Diagnosis of Neurodegenerative Diseases
- A RANGE OF TREATMENT FOR THE NEURODEGENERATIVE DISEASES
- The Modern System of Medicine
- Medical Management
- Surgical Management
- Emerging Management
- Ayush or Indian System of Medicine
- RECENT ADVANCEMENT IN THE AYURVEDIC MANAGEMENT OF NEURODEGENERATIVE DISEASES
- Ayurvedic/herbal Medicinal Plants
- Different Actions of an Extract Derived from Ayurvedic Medicinal Plants
- Herbo-mineral Drugs
- Panchkarma (Bio-purification Procedures)
- Overview of Panchkarma Therapy
- Studies Conducted in Different Panchkarma Procedures
- CONCLUDING REMARKS
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
- Role of Phytochemicals in Neurodegenerative Disorders.
- Shambhoo Sharan Tripathi1,*, Raushan Kumar1, Prabhash Kumar Pandey1, Abhishek Kumar Singh2 and Nidhi Gupta3,4
- INTRODUCTION
- PATHOGENESIS OF NEURODEGENERATION
- ROLE OF PHYTOCHEMICALS IN NEURODEGENERATION
- NERUROPROTECTING PHYTOCHEMICALS
- Epigallocatechin-3-Gallate
- Berberine
- Curcumin
- Resveratrol
- Quercetin
- Fisetin
- Ginsenosides
- Sulforaphane (SFN)
- Genistein
- Allium and Allicin
- Icariin
- Morin
- Baicalein
- CONCLUSIONS
- FUTURE SUGGESTION
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
- Therapeutic Potential of Vitamins in Parkinson's Disease
- Prabhash Kumar Pandey1,2,*, Shambhoo Sharan Tripathi1, Jayant Dewangan2, Ranjan Singh3, Farrukh Jamal4 and Srikanta Kumar Rath2
- INTRODUCTION
- ROLE OF OXIDATIVE STRESS IN THE PATHOGENESIS OF PD
- THEATRICAL ROLE OF NEUROINFLAMMATION IN THE PATHOGENESIS OF PD
- NEUROPROTECTIVE ROLES OF VITAMINS IN THE TREATMENT OF PARKINSONISM
- Neuroprotective Role of Vitamin B in PD
- Usability of Vitamin C in PD Treatment
- Role of Vitamin E in the Treatment of Pd
- Role of Vitamin D as a Neuroprotectant in the Pd Treatment
- CONCLUSION AND FUTURE DIRECTIONS
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
- Potential of Gut Microbiome in the Diagnosis and Treatment of Alzheimer's and Parkinson's Disease
- Nilofar Khan1 and Ravishankar Patil1,*
- INTRODUCTION
- ALZHEIMER'S DISEASE: PATHOMECHANISM, PREVALENCE, SYMPTOMS, AND TREATMENT
- Prevalence of AD
- Symptoms of AD
- Causes of AD
- Treatment Strategies for AD
- Acetylcholine Esterase (Ache)
- β Secretase
- ϒ Secretase
- Aβ Vaccination
- Amyloid Anti-Aggregation Therapies
- Anti-Inflammatory Drugs
- Cholesterol-Lowering Drugs
- PARKINSON'S DISEASE: PATHOMECHANISM, PREVALENCE, SYMPTOMS, AND TREATMENT
- Prevalence of PD.
- Symptoms of PD
- Treatment Strategies for PD
- Dopamine Replacement Therapy (DRT)
- L-DOPA: Promising DRT for PD
- Anti-inflammatory Agents and Protein Anti-Aggregants
- ROLE OF GUT MICROBIOME IN METABOLISM AND HEALTH
- Role of Prebiotics in Gut Microflora Balance
- Gut Microbiome and Neurodegenerative Disease
- Gut and Alzheimer's Disease
- Therapeutic Role of Probiotics in AD
- Prebiotics For AD
- Gut Microbiome and Parkinson's Disease
- Probiotics and Prebiotics for PD
- Mediterranean Diet
- Ketogenic Diet and Fasting
- Polyphenols
- CONCLUDING REMARKS
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
- Therapeutic Efficacy of Mushroom in Neurodegenerative Diseases
- Ankita Kushwaha1,*, Vivek K. Chaturvedi2, Sachchida Nand Rai2, Sanjay C. Masih3 and M. P. Singh2
- INTRODUCTION
- NEUROPROTECTIVE EFFECTS OF MUSHROOMS AGAINST NEURODEGENERATIVE DISEASE
- ADVANTAGEOUS EFFECTS OF MUSHROOMS AGAINST NDS
- Role of Mushrooms in Alzheimer's Disease (AD)
- Mushrooms Having Beneficial Effects Against Parkinson's Pisease (PD)
- CONCLUSIONS
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
- Advances in Experimental Animal Models Provide Insights into Different Etiology and Mechanism of Multiple Sclerosis to Design Therapeutics
- Sourodip Sengupta and Jayasri Das Sarma*
- INTRODUCTION
- CLASSIFICATION OF MS
- ETIOLOGY OF MS
- CLINICAL SYMPTOMS AND DIAGNOSIS
- PRESENT THERAPEUTICS AND LIMITATIONS
- EXPERIMENTAL ANIMAL MODELS TO UNDERSTAND THE MECHANISMS OF MS
- EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS (EAE)
- EXPERIMENTAL VIRAL-INDUCED MODEL OF MS
- TMEV MODEL
- MHV MODEL
- MHV MEDIATED IMMUNE RESPONSES
- Recombinant Demyelinating (DM) And Non-Demyelinating (NDM) Mhv Strains
- CONCLUDING REMARKS
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST.
- ACKNOWLEDGEMENTS
- REFERENCES
- Novel Therapeutic Targets in Amyotrophic Lateral Sclerosis
- Priyanka Gautam, Mukesh Kumar Jogi and Abhishek Pathak*
- INTRODUCTION
- HISTORY
- EPIDEMIOLOGY
- SIGN AND SYMPTOMS
- CLINICAL CHARACTERISTICS
- GENETICS
- MUTATION
- ALS PATHOGENIC PATHWAYS AS THERAPEUTIC TARGETS
- TARGETING OXIDATIVE STRESS
- TARGETING GLUTAMATE TRANSPORT
- TARGETING PROTEIN AGGREGATION
- TARGETING MITOCHONDRIAL DYSFUNCTION
- TARGETING APOPTOSIS
- TARGETING NEUROINFLAMMATION
- TARGETING GLIAL CELLS (MICROGLIA AND ASTROCYTES)
- TARGETING DYSREGULATED RNA PROCESS
- TARGETING NEUROMUSCULAR JUNCTION
- TARGETING GENE
- CONCLUDING REMARKS
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
- Impact of Nano-Formulations of Natural Compounds in the Management of Neuro degenerative Diseases
- Hemraj Heer1, Vishav Prabhjot Kaur1, Tania Bajaj1, Arti Singh2, Priyanka Bajaj3 and Charan Singh1,*
- INTRODUCTION
- NEUROPROTECTIVE POTENTIAL OF NATURAL PRODUCTS
- APPROACHES FOR CNS TARGETED NATURAL COMPOUNDS DELIVERY
- NANO-BASED DELIVERY SYSTEMS FOR NEURODEGENERATIVE DISORDERS
- LIPIDIC NANOMATERIALS
- Liposomes
- Solid Lipid Nanoparticles and Nanostructured Lipid Carrier Systems
- Carbon Nanomaterials
- Carbon Nanotubes
- Nanodiamonds
- Polymeric Systems
- Dendrimers
- Metal-organic Frameworks (MOFs)
- Semiconducting Nanoparticles And Quantum Dots
- Phospholipid Complexes
- METHODS OF NANOFORMULATIONS PREPARATION
- Emulsion-solvent Evaporation Method
- Solvent Diffusion Method
- Salting Out Method
- Supercritical Fluid Technique
- Polymerization Technique
- NATURAL COMPOUNDS NANO-DELIVERY IN NEURO DEGENERATIVE DISEASES
- Alzheimer's Disease
- Huntington's Disease
- Parkinson's Disease
- CONCLUSION
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS.
- REFERENCES
- Recent Advancement in the Nanoparticles Mediated Therapeutics of Parkinson's Disease
- Vivek K. Chaturvedi1, Payal Singh2 and M.P. Singh1,*
- INTRODUCTION
- NANOPARTICLES BASED THERAPY FOR PARKINSON'S DISEASE
- CONCLUSION
- CONSENT FOR PUBLICATION
- CONFLICT OF INTEREST
- ACKNOWLEDGEMENTS
- REFERENCES
- Subject Index.