Organotypic Models in Drug Development [E-Book] /

Organotypic Models in Drug Development [E-Book] / edited by Monika Schäfer-Korting, Silvya Stuchi Maria-Engler, Robert Landsiedel.

This book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major inte...

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Landsiedel, Robert, editor
Schäfer-Korting, Monika, editor / Stuchi Maria-Engler, Silvya, editor
1st edition 2021.
Cham : Springer, 2021
VIII, 323 pages 70 illustrations, 37 illustrations in color (online resource)
englisch
9783030700638
10.1007/978-3-030-70063-8
Handbook of Experimental Pharmacology ; 265
Medical genetics.
Pathology.
Pharmacology.


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505 0 |a Inflammatory skin disease models in vitro and in animals - predictability for drug development -- Neural In Vitro Models for Studying Substances Acting on the Central Nervous System -- Quality of commercial tissues Standardised Reconstructed Skin Models in Toxicology and Pharmacology: State of the Art and Future Development -- Human-Derived In Vitro Models Used for Skin Toxicity Testing Under REACh -- Disease Models: Lung models for testing drugs against inflammation and infection -- In Vitro Models of the Blood-Brain Barrier -- How Qualification of 3D Disease Models Cuts the Gordian Knot in Preclinical Drug Development -- The CAM Assay as an Alternative In Vivo Model for Drug Testing -- Organotypic Models in Drug Development "Tumor Models and Cancer Systems Biology for the Investigation of Anticancer Drugs and Resistance Development -- Tissue Engineering for Musculoskeletal Regeneration and Disease Modeling -- Immunocompetent human intestinal models in preclinical drug development -- EngineeredHeart Muscle Models in Phenotypic Drug Screens. 
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