This title appears in the Scientific Report :
2010
Please use the identifier:
http://dx.doi.org/10.1016/j.tet.2010.10.036 in citations.
Efficient synthesis of fluorobenzyl-oxoimidazolidinone derivatives: Precursors for the radiosynthesis of [18F]fluorophenylamino acids
Efficient synthesis of fluorobenzyl-oxoimidazolidinone derivatives: Precursors for the radiosynthesis of [18F]fluorophenylamino acids
This paper describes an efficient synthesis of fluorobenzyloxoimidazolidinone derivatives. The title compounds 1a, 1b and 1c could be prepared with high diasteromeric purity (>99%) and overall yields of 19%, 48% and 41% in a ten or six-step synthetic procedure, respectively. These compounds are u...
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Personal Name(s): | Castillo Meleán, J. |
---|---|
Ermert, J. / Coenen, H. H. | |
Contributing Institute: |
Nuklearchemie; INM-5 |
Published in: | Tetrahedron, 66 (2010) S. 9996 - 10001 |
Imprint: |
Amsterdam [u.a.]
Elsevier Science
2010
|
Physical Description: |
9996 - 10001 |
DOI: |
10.1016/j.tet.2010.10.036 |
Document Type: |
Journal Article |
Research Program: |
(Dys-)function and Plasticity Funktion und Dysfunktion des Nervensystems |
Series Title: |
Tetrahedron
66 |
Subject (ZB): | |
Publikationsportal JuSER |
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500 | |a The authors want to thank Dr. S. Willbold, Dr. D. Hofmann and Dr. M. Holschbach for recording the spectroscopic data. This work was supported by a Grant of the Technology Transfer Bureau of FZ-Julich. | ||
520 | |a This paper describes an efficient synthesis of fluorobenzyloxoimidazolidinone derivatives. The title compounds 1a, 1b and 1c could be prepared with high diasteromeric purity (>99%) and overall yields of 19%, 48% and 41% in a ten or six-step synthetic procedure, respectively. These compounds are used as precursors for isotopic F-18-labelling. (c) 2010 Elsevier Ltd. All rights reserved. | ||
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