This title appears in the Scientific Report :
2012
Please use the identifier:
http://dx.doi.org/10.1039/c0sm00683a in citations.
Please use the identifier: http://hdl.handle.net/2128/7257 in citations.
Exploring internal protein dynamics by neutron spin echo spectroscopy
Exploring internal protein dynamics by neutron spin echo spectroscopy
The activity of proteins is often related to configuration changes that concern single atoms or amino acids or entire subdomains within the protein. The corresponding length and timescale reach from sub-Angstrom and picoseconds to nanometers and several tens of nanoseconds and beyond. We focus here...
| Personal Name(s): | Biehl, R. |
|---|---|
| Monkenbusch, M. / Richter, D. | |
| Contributing Institute: |
Neutronenstreuung; ICS-1 JCNS; JCNS |
| Published in: | Soft matter, 7 (2011) S. 1299 - 1307 |
| Imprint: |
Cambridge
Royal Society of Chemistry (RSC)
2011
|
| Physical Description: |
1299 - 1307 |
| DOI: |
10.1039/c0sm00683a |
| Document Type: |
Journal Article |
| Research Program: |
Großgeräte für die Forschung mit Photonen, Neutronen und Ionen (PNI) BioSoft: Makromolekulare Systeme und biologische Informationsverarbeitung |
| Series Title: |
Soft Matter
7 |
| Subject (ZB): | |
| Link: |
Get full text Published under German "Allianz" Licensing conditions on 2010-11-15. Available in OpenAccess from 2011-11-15 |
| Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/7257 in citations.
|
The activity of proteins is often related to configuration changes that concern single atoms or amino acids or entire subdomains within the protein. The corresponding length and timescale reach from sub-Angstrom and picoseconds to nanometers and several tens of nanoseconds and beyond. We focus here on the slow motions on several ten nanosecond timescales of complete domains and show that and how these can be accessed by means of small angle neutron scattering and neutron spin-echo spectroscopy. In particular neutron spin echo spectroscopy is able to access timescales up to several hundred nanoseconds. Further insight into domain dynamics can be achieved by modelling the dynamics in comparison with the experimental data. |