This title appears in the Scientific Report :
2010
Please use the identifier:
http://dx.doi.org/10.1007/s00115-010-3105-6 in citations.
Strukturelle und funktionelle Bildgebung zur Pathophysiologie der Apraxie
Strukturelle und funktionelle Bildgebung zur Pathophysiologie der Apraxie
A better understanding of the neural bases of apraxia is an important prerequisite to develop new therapeutic strategies for the disabling apraxic deficits after left-hemisphere stroke, like disturbed imitation of gestures, deficient pantomime, and object use deficits. Recently, functional and struc...
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Personal Name(s): | Weiss, P.H. |
---|---|
Fink, G.R. | |
Contributing Institute: |
Kognitive Neurowissenschaften; INM-3 |
Published in: | Der @Nervenarzt, 81 (2010) S. 1444 - 1449 |
Imprint: |
Berlin
Springer
2010
|
Physical Description: |
1444 - 1449 |
PubMed ID: |
21088821 |
DOI: |
10.1007/s00115-010-3105-6 |
Document Type: |
Journal Article |
Research Program: |
(Dys-)function and Plasticity Funktion und Dysfunktion des Nervensystems |
Series Title: |
Nervenarzt
81 |
Subject (ZB): | |
Publikationsportal JuSER |
A better understanding of the neural bases of apraxia is an important prerequisite to develop new therapeutic strategies for the disabling apraxic deficits after left-hemisphere stroke, like disturbed imitation of gestures, deficient pantomime, and object use deficits. Recently, functional and structural imaging methods allowed deeper insights into the pathophysiology of apraxia: While apraxic object use deficits result from the dysfunction of an extended fronto-parietal network within the left hemisphere, pantomime deficits are caused by impaired functioning of the left inferior frontal cortex. Further apraxia-related, motor cognitive processes (i.e., gesture imitation, integration of temporal and spatial movement information, and intentional movement planning) depend on the integrity of the left parietal cortex. Newly developed functional and structural imaging methods, like dynamic causal modelling (DCM) and diffusion tensor imaging (DTI), promise to further elucidate the pathophysiology of apraxia at the network level. |