Theory of Coherent and Incoherent Nuclear Spin Dephasing in the Heart
Theory of Coherent and Incoherent Nuclear Spin Dephasing in the Heart
We present an analytical theory of susceptibility induced nuclear spin dephasing in the capillary network of myocardium. Using a strong collision approach, equations are obtained for the relaxation rate of the free induction and the spin echo decay. Simulation and experimental data are well predicte...
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Personal Name(s): | Bauer, Wolfgang (Corresponding Author) |
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Nadler, Walter / Bock, Michael / Schad, Lothar / Wacker, Christian / Hartlep, Andreas / Ertl, Georg | |
Contributing Institute: |
John von Neumann - Institut für Computing; NIC |
Published in: | Physical review letters, 83 (1999) 20, S. 4215 - 4218 |
Imprint: |
College Park, Md.
APS
1999
|
DOI: |
10.1103/PhysRevLett.83.4215 |
Document Type: |
Journal Article |
Research Program: |
ohne Topic |
Link: |
OpenAccess |
Publikationsportal JuSER |
Please use the identifier: http://dx.doi.org/10.1103/PhysRevLett.83.4215 in citations.
We present an analytical theory of susceptibility induced nuclear spin dephasing in the capillary network of myocardium. Using a strong collision approach, equations are obtained for the relaxation rate of the free induction and the spin echo decay. Simulation and experimental data are well predicted by the theory. Since paramagnetic deoxyhemoglobin as the origin of nuclear spin dephasing has a higher tissue concentration in myocardium supplied by a stenotic, i.e., significantly narrowed, coronary artery, spin dephasing might serve as a diagnostic tool. Our approach can be modified for capillary networks in other tissues than myocardium and may be applied in material science. |