This title appears in the Scientific Report : 2014 

Brain networks of perceptual decision-making: an fMRI ALE meta-analysis
Keuken, Max C. (Corresponding Author)
Müller-Axt, Christa / Langner, Robert / Eickhoff, Simon / Forstmann, Birte U. / Neumann, Jane
Strukturelle und funktionelle Organisation des Gehirns; INM-1
Frontiers in human neuroscience, 8 (2014) S. 445
Lausanne Frontiers Research Foundation 2014
10.3389/fnhum.2014.00445
24994979
Journal Article
Connectivity and Activity
Pathophysiological Mechanisms of Neurological and Psychiatric Diseases
OpenAccess
Please use the identifier: http://dx.doi.org/10.3389/fnhum.2014.00445 in citations.
Please use the identifier: http://hdl.handle.net/2128/11520 in citations.
In the recent perceptual decision-making literature, a fronto-parietal network is typically reported to primarily represent the neural substrate of human perceptual decision-making. However, the view that only cortical areas are involved in perceptual decision-making has been challenged by several neurocomputational models which all argue that the basal ganglia play an essential role in perceptual decisions. To consolidate these different views, we conducted an Activation Likelihood Estimation (ALE) meta-analysis on the existing neuroimaging literature. The results argue in favor of the involvement of a frontal-parietal network in general perceptual decision-making that is possibly complemented by the basal ganglia, and modulated in substantial parts by task difficulty. In contrast, expectation of reward, an important aspect of many decision-making processes, shows almost no overlap with the general perceptual decision-making network.