This title appears in the Scientific Report :
2012
Please use the identifier:
http://dx.doi.org/10.1002/elps.201100682 in citations.
Nonaqueous capillary electrophoresis–mass spectrometry: A versatile, straightforward tool for the analysis of alkaloids from psychoactive plant extracts
Nonaqueous capillary electrophoresis–mass spectrometry: A versatile, straightforward tool for the analysis of alkaloids from psychoactive plant extracts
In this study we show that a nonaqueous capillary electrophoresis mass spectrometry (NACE-MS) method carefully optimized by a design of experiment can be applied to a very large number of alkaloids in different plant extracts. It is possible to characterize the pattern of the psychoactive alkaloids...
Saved in:
Personal Name(s): | Posch, T.N. |
---|---|
Martin, N. / Pütz, M. / Huhn, C. | |
Contributing Institute: |
Zentralabteilung für Chemische Analysen; ZCH |
Published in: | Electrophoresis, 33 (2012) S. 1557 - 1566 |
Imprint: |
Weinheim
Wiley-Blackwell
2012
|
Physical Description: |
1557 - 1566 |
PubMed ID: |
22736357 |
DOI: |
10.1002/elps.201100682 |
Document Type: |
Journal Article |
Research Program: |
Techniken, Innovation und Gesellschaft (TIG) |
Series Title: |
Electrophoresis
33 |
Subject (ZB): | |
Publikationsportal JuSER |
In this study we show that a nonaqueous capillary electrophoresis mass spectrometry (NACE-MS) method carefully optimized by a design of experiment can be applied to a very large number of alkaloids in different plant extracts. It is possible to characterize the pattern of the psychoactive alkaloids in several plant samples and preparations thereof, each presenting different challenges in their analysis. The method is shown to be able to separate structurally closely related substances, diastereomers and further isobaric compounds, to separate members of different alkaloid classes within one run and to tolerate significant matrix load. A comparison with methods presented in the literature reveals that a near-generic NACE-MS method for the fast profiling of alkaloids in forensically relevant plant samples has been developed. |