This title appears in the Scientific Report :
2015
Please use the identifier:
http://dx.doi.org/10.1038/srep13222 in citations.
Please use the identifier: http://hdl.handle.net/2128/9555 in citations.
QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers
QIAD assay for quantitating a compound’s efficacy in elimination of toxic Aβ oligomers
Strong evidence exists for a central role of amyloid β-protein (Aβ) oligomers in the pathogenesis of Alzheimer’s disease. We have developed a fast, reliable and robust in vitro assay, termed QIAD, to quantify the effect of any compound on the Aβ aggregate size distribution. Applying QIAD, we studied...
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Personal Name(s): | Brener, Oleksandr |
---|---|
Dunkelmann, Tina / Gremer, Lothar / van Groen, Thomas / Mirecka, Ewa A. / Kadish, Inga / Willuweit, Antje / Kutzsche, Janine / Jürgens, Dagmar / Rudolph, Stephan / Tusche, Markus / Bongen, Patrick / Pietruszka, Jörg / Oesterhelt, Filipp / Langen, Karl-Josef / Demuth, Hans-Ulrich / Janssen, Arnold / Hoyer, Wolfgang / Funke, Susanne A. / Nagel-Steger, Luitgard / Willbold, Dieter (Corresponding author) | |
Contributing Institute: |
Biotechnologie; IBG-1 Institut für Bioorganische Chemie (HHUD); IBOC Strukturbiochemie; ICS-6 |
Published in: | Scientific reports, 5 (2015) S. 13222 |
Imprint: |
London
Nature Publishing Group
2015
|
DOI: |
10.1038/srep13222 |
PubMed ID: |
26394756 |
Document Type: |
Journal Article |
Research Program: |
Biotechnology Physical Basis of Diseases |
Link: |
Get full text OpenAccess OpenAccess |
Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/9555 in citations.
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