This title appears in the Scientific Report :
2015
Please use the identifier:
http://dx.doi.org/10.1093/bioinformatics/btu170 in citations.
Please use the identifier: http://hdl.handle.net/2128/9693 in citations.
Trimmomatic: a flexible trimmer for Illumina sequence data
Trimmomatic: a flexible trimmer for Illumina sequence data
Motivation: Although many next-generation sequencing (NGS) read preprocessing tools already existed, we could not find any tool or combination of tools that met our requirements in terms of flexibility, correct handling of paired-end data and high performance. We have developed Trimmomatic as a more...
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Personal Name(s): | Bolger, A. M. |
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Lohse, M. / Usadel, Björn (Corresponding author) | |
Contributing Institute: |
Pflanzenwissenschaften; IBG-2 |
Published in: | Bioinformatics, 30 (2014) 15, S. 2114 - 2120 |
Imprint: |
Oxford
Oxford Univ. Press
2014
|
DOI: |
10.1093/bioinformatics/btu170 |
PubMed ID: |
24695404 |
Document Type: |
Journal Article |
Research Program: |
Plant Science |
Link: |
OpenAccess OpenAccess |
Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/9693 in citations.
Motivation: Although many next-generation sequencing (NGS) read preprocessing tools already existed, we could not find any tool or combination of tools that met our requirements in terms of flexibility, correct handling of paired-end data and high performance. We have developed Trimmomatic as a more flexible and efficient preprocessing tool, which could correctly handle paired-end data.Results: The value of NGS read preprocessing is demonstrated for both reference-based and reference-free tasks. Trimmomatic is shown to produce output that is at least competitive with, and in many cases superior to, that produced by other tools, in all scenarios tested. |