This title appears in the Scientific Report :
2015
Please use the identifier:
http://dx.doi.org/10.1016/j.snb.2014.10.058 in citations.
An application of field-effect sensors for in-situ monitoring of degradation of biopolymers
An application of field-effect sensors for in-situ monitoring of degradation of biopolymers
The characterization of the degradation kinetics of biodegradable polymers is mandatory with regard to their proper application. In the present work, polymer-modified electrolyte–insulator–semiconductor (PMEIS) field-effect sensors have been applied for in-situ monitoring of the pH-dependent degrada...
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Personal Name(s): | Schusser, S. |
---|---|
Poghossian, A. / Bäcker, M. / Krischer, M. / Leinhos, M. / Wagner, P. / Schöning, Michael J. (Corresponding author) | |
Contributing Institute: |
Bioelektronik; PGI-8 |
Published in: |
Sensors and actuators |
Imprint: |
Amsterdam [u.a.]
Elsevier Science
2015
|
DOI: |
10.1016/j.snb.2014.10.058 |
Document Type: |
Journal Article |
Research Program: |
Controlling Configuration-Based Phenomena |
Publikationsportal JuSER |
The characterization of the degradation kinetics of biodegradable polymers is mandatory with regard to their proper application. In the present work, polymer-modified electrolyte–insulator–semiconductor (PMEIS) field-effect sensors have been applied for in-situ monitoring of the pH-dependent degradation kinetics of the commercially available biopolymer poly(d,l-lactic acid) (PDLLA) in buffer solutions from pH 3 to pH 13. PDLLA films of 500 nm thickness were deposited on the surface of an Al–p-Si–SiO2–Ta2O5 structure from a polymer solution by means of spin-coating method. The PMEIS sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. A faster degradation has been observed for PDLLA films exposed to alkaline solutions (pH 9, pH 11 and pH 13). |