This title appears in the Scientific Report : 2003 

Benzaldehyde lyase-catalyzed enantioselective carboligation of aromatic aldehydes with mono- and dimethoxy acetaldehyde
Demir, A. S.
Sesenoglu, Ö. / Dünkelmann, P. / Müller, M.
Biotechnologie 2; IBT-2
Organic letters, 5 (2003) S. 2047 - 2050
Washington, DC ACS 2003
2047 - 2050
12790525
10.1021/ol034415b
Journal Article
Biotechnologie
Organic Letters 5
J
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OpenAccess
Please use the identifier: http://hdl.handle.net/2128/2435 in citations.
Please use the identifier: http://dx.doi.org/10.1021/ol034415b in citations.
[reaction: see text] Benzaldehyde lyase from the Pseudomonas fluorescens catalyzes the reaction of aromatic aldehydes with methoxy and dimethoxy acetaldehyde and furnishes (R)-2-hydroxy-3-methoxy-1-arylpropan-1-one and (R)-2-hydroxy-3,3-dimethoxy-1-arylpropan-1-one in high yields and enantiomeric excess via acyloin linkage. Aromatic aldehydes and benzoins are converted into enamine-carbanion-like intermediates prior to carboligation.