This title appears in the Scientific Report :
2003
Please use the identifier:
http://dx.doi.org/10.1016/S0028-3932(03)00125-8 in citations.
Activation of Broca's area during the production of spoken and signed language: a combined cytoarchitectonic mapping and PET analysis
Activation of Broca's area during the production of spoken and signed language: a combined cytoarchitectonic mapping and PET analysis
Broca's area in the inferior frontal gyrus consists of two cytoarchitectonically defined regions-Brodmann areas (BA) 44 and 45. Combining probabilistic maps of these two areas with functional neuroimaging data obtained using PET, it is shown that BA45, not BA44, is activated by both speech and...
Saved in:
Personal Name(s): | Horwitz, B. |
---|---|
Amunts, K. / Bhattacharyya, R. / Parkin, D. / Jeffries, K. / Zilles, K. / Braun, A. R. | |
Contributing Institute: |
Institut für Medizin; IME |
Published in: | Neuropsychologia, 41 (2003) S. 1868 - 1876 |
Imprint: |
Amsterdam [u.a.]
Elsevier Science
2003
|
Physical Description: |
1868 - 1876 |
PubMed ID: |
14572520 |
DOI: |
10.1016/S0028-3932(03)00125-8 |
Document Type: |
Journal Article |
Research Program: |
Neurowissenschaften |
Series Title: |
Neuropsychologia
41 |
Subject (ZB): | |
Publikationsportal JuSER |
Broca's area in the inferior frontal gyrus consists of two cytoarchitectonically defined regions-Brodmann areas (BA) 44 and 45. Combining probabilistic maps of these two areas with functional neuroimaging data obtained using PET, it is shown that BA45, not BA44, is activated by both speech and signing during the production of language narratives in bilingual subjects fluent from early childhood in both American Sign Language (ASL) and English when the generation of complex movements and sounds is taken into account. It is BA44, not BA45, that is activated by the generation of complex articulatory movements of oral/laryngeal or limb musculature. The same patterns of activation are found for oral language production in a group of English speaking monolingual subjects. These findings implicate BA45 as the part of Broca's area that is fundamental to the modality-independent aspects of language generation. Published by Elsevier Ltd. |