This title appears in the Scientific Report :
2005
Please use the identifier:
http://dx.doi.org/10.1016/j.bbamem.2005.07.006 in citations.
Specific volumes of unsaturated phosphatidylcholines in the liquid crystalline lamellar phase
Specific volumes of unsaturated phosphatidylcholines in the liquid crystalline lamellar phase
The specific volumes of seven 1,2-diacyl-sn-glycero-3-phosphocholines with symmetric, unbranched acyl chains containing one, four, or six cis double bonds per chain, or with a saturated sn-1 chain and one, four, or six cis double bonds in the sn-2 chain were determined by the neutral buoyancy method...
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Personal Name(s): | Koenig, B. W. |
---|---|
Gawrisch, K. | |
Contributing Institute: |
Biologische Strukturforschung; IBI-2 |
Published in: | Biochimica et biophysica acta / Biomembranes, 1715 (2005) S. 65 - 70 |
Imprint: |
Amsterdam
Elsevier
2005
|
Physical Description: |
65 - 70 |
PubMed ID: |
16109383 |
DOI: |
10.1016/j.bbamem.2005.07.006 |
Document Type: |
Journal Article |
Research Program: |
Neurowissenschaften |
Series Title: |
BBA - Biomembranes
1715 |
Subject (ZB): | |
Publikationsportal JuSER |
The specific volumes of seven 1,2-diacyl-sn-glycero-3-phosphocholines with symmetric, unbranched acyl chains containing one, four, or six cis double bonds per chain, or with a saturated sn-1 chain and one, four, or six cis double bonds in the sn-2 chain were determined by the neutral buoyancy method. Experiments were conducted in the liquid crystalline lamellar phase over the temperature range from 5 to 35 degrees C. It is demonstrated that the molecular volume of phosphatidylcholines can be well approximated as the sum of a constant volume of the polar lipid head region and the temperature-dependent volumes of hydrocarbon chain CH2, CH, and terminal CH3 groups. A linear dependence of chain segment volumes on temperature was observed. A self-consistent set of partially temperature-dependent volumes is obtained that allows prediction of phosphatidylcholine molecular volumes within very tight error margins. |