This title appears in the Scientific Report :
2006
Please use the identifier:
http://dx.doi.org/10.1016/j.ijms.2005.11.001 in citations.
On-line isotope dilution in laser ablation inductively coupled plasma mass spectrometry using a microflow nebulizer inserted in the laser ablation chamber
On-line isotope dilution in laser ablation inductively coupled plasma mass spectrometry using a microflow nebulizer inserted in the laser ablation chamber
Laser ablation ICP-MS (inductively coupled plasma mass spectrometry) is becoming one of the most important analytical techniques for fast determination of trace impurities in solid samples. Quantification of analytical results requires matrix-matched standards, which are in some cases (e.g., high-pu...
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Personal Name(s): | Pickhardt, C. |
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Izmer, A. V. / Zoriy, M. V. / Schaumlöffel, D. / Becker, J. S. | |
Contributing Institute: |
Abteilung Sicherheit und Strahlenschutz; S Zentralabteilung für Chemische Analysen; ZCH |
Published in: | International journal of mass spectrometry, 248 (2006) S. 136 - 141 |
Imprint: |
[S.l.]
Elsevier Science
2006
|
Physical Description: |
136 - 141 |
DOI: |
10.1016/j.ijms.2005.11.001 |
Document Type: |
Journal Article |
Research Program: |
Terrestrische Umwelt |
Series Title: |
International Journal of Mass Spectrometry
248 |
Subject (ZB): | |
Publikationsportal JuSER |
Laser ablation ICP-MS (inductively coupled plasma mass spectrometry) is becoming one of the most important analytical techniques for fast determination of trace impurities in solid samples. Quantification of analytical results requires matrix-matched standards, which are in some cases (e.g., high-purity metals, proteins separated by 2D gel electrophoresis) difficult to obtain or prepare. In order to overcome the quantification problem a special arrangement for on-line solution-based calibration has been proposed in laser ablation ICP-MS by the insertion of a microflow nebulizer in the laser ablation chamber. This arrangement allows an easy, accurate and precise quantification by on-line isotope dilution using a defined standard solution with an isotope enriched tracer nebulized to the laser-ablated sample material. An ideal matrix matching in LA-ICP-MS is therefore obtained during the measurement. The figures of merit of this arrangement with a microflow nebulizer inserted in the laser ablation chamber and applications of on-line isotope dilution in LA-ICP-MS on two different types of sample material (NIST glass SRM 612 and NIST apple leaves SRM 1515) will be described. (c) 2005 Elsevier B.V. All rights reserved. |