Description: Nuclear data for production of Y-88, Nd-140, Sm-153 and Yb-169 via novel routes

This title appears in the Scientific Report : 2007

Nuclear data for production of Y-88, Nd-140, Sm-153 and Yb-169 via novel routes

The possibilities of production of the therapy-related radionuclides Nd-140, Sm-153 and Yb-169, and of Y-88, in no-carrier-added form were investigated. For Y-88 production the nuclear processes Sr-nat(p, xn)Y-88 and Rb-nat(alpha, xn)Y-88 over the energy ranges E-p = 14 -> 9 MeV and E-alpha = 18...

Personal Name(s):	Qaim, S. M.
	Spahn, I. / Kandil, S. A. / Coenen, H. H.
Contributing Institute:	Nuklearchemie; INB-4
Published in:	Radiochimica acta, 95 (2007) S. 313 - 317
Imprint:	MÃ¼nchen Oldenbourg 2007
Physical Description:	313 - 317
DOI:	10.1524/ract.2007.95.6.313
Document Type:	Journal Article
Research Program:	Funktion und Dysfunktion des Nervensystems
Series Title:	Radiochimica Acta 95
Subject (ZB):	J
Link:	Get full text OpenAccess
	Publikationsportal JuSER

Please use the identifier: http://hdl.handle.net/2128/18306 in citations.
Please use the identifier: http://dx.doi.org/10.1524/ract.2007.95.6.313 in citations.

The possibilities of production of the therapy-related radionuclides Nd-140, Sm-153 and Yb-169, and of Y-88, in no-carrier-added form were investigated. For Y-88 production the nuclear processes Sr-nat(p, xn)Y-88 and Rb-nat(alpha, xn)Y-88 over the energy ranges E-p = 14 -> 9 MeV and E-alpha = 18 -> 12 MeV, respectively, can be utilised, although the former reaction is superior, both in terms of yield and radionuclidic purity. For Nd-140 production the reactions Pr-141(p, 2n)Nd-140 and Ce-nat(He-3, xn)Nd-140 were investigated in detail. The optimum energy ranges are E-P = 30 -> 15 MeV and E-3He = 35 -> 20 MeV. respectively. Both processes yield high-purity Nd-140. The former reaction, however, leads to a product yield about 17 times higher than the latter reaction, and is therefore to be preferred. In the case of (SM)-S-153, investigations were done on the Eu-153(n, p)Sm-153 reaction with 14 MeV d(Be) neutrons as well as on the Nd-150(alpha, n)Sm-153 reaction. The yield of the (n, p) reaction is very low, but the (alpha, n) reaction over the energy range E-alpha = 25 -> 15 MeV offers a good potential for production of no-carrier-added (SM)-S-153 in quantities sufficient for therapeutic applications. Also for the radionuclide Yb-169 a novel route, viz. Tm-169(p, n)Yb-169 reaction, was investigated. A critical comparison of this route with the commonly used (n, gamma) route, however, showed that, due to the much higher cost involved, the (p, n) process should be utilised only when there is a real need of the high specific radioactivity product.