Description: Structural and functional MRI-findings in children and adolescents with antisocial behavior

This title appears in the Scientific Report : 2008

Structural and functional MRI-findings in children and adolescents with antisocial behavior

BACKGROUND: The developmental course of children with conduct disorder (CD) is heterogeneous. Especially children who exhibit symptoms early in their lifetimes are characterized by a negative outcome. Neurobiological aspects of CD have been investigated in these children but little is known about st...

Personal Name(s):	Vloet, T. D.
	Konrad, K. / Huebner, T. / Herpertz, S. / Herpertz-Dahlmann, B.
Contributing Institute:	Institut für Neurowissenschaften und Biophysik - Medizin; INB-3 JARA-BRAIN; JARA-BRAIN
Published in:	Behavioral sciences & the law, 26 (2008) S. 99 - 111
Imprint:	Chichester [u.a.] Wiley 2008
Physical Description:	99 - 111
PubMed ID:	18327828
DOI:	10.1002/bsl.794
Document Type:	Journal Article
Research Program:	Funktion und Dysfunktion des Nervensystems
Series Title:	Behavioral Sciences and the Law 26
Subject (ZB):	Adolescent Adolescent Behavior: psychology Antisocial Personality Disorder: complications Antisocial Personality Disorder: psychology Child Child Behavior: psychology Conduct Disorder: complications Conduct Disorder: physiopathology Conduct Disorder: radiography Forensic Psychiatry Humans Magnetic Resonance Imaging Risk Factors
	Publikationsportal JuSER

Please use the identifier: http://dx.doi.org/10.1002/bsl.794 in citations.

BACKGROUND: The developmental course of children with conduct disorder (CD) is heterogeneous. Especially children who exhibit symptoms early in their lifetimes are characterized by a negative outcome. Neurobiological aspects of CD have been investigated in these children but little is known about structural and functional brain aberrations. METHODS: We describe the developmental taxonomy of children with CD and focus on those with the early onset subtype. Structural MRI data of these children and antisocial adults are recapitulated. The impact of investigating neurobiological underpinnings of antisocial behavior and how this might contribute to future forensic and psychiatric assessments is discussed. RESULTS/ CONCLUSION: Children display similar structural aberrations of fronto-limbic structures to adults with antisocial behavior, and amygdala dysfunction might be closely related to dysregulated emotions. Though the investigation of biological factors in antisocial subjects has made great progress in recent years, today MRI is still a rather complex, expensive and indistinct method for forensic assessment.