This title appears in the Scientific Report :
2008
Please use the identifier:
http://dx.doi.org/10.1007/s00203-008-0351-0 in citations.
Corynebacterium glutamicum possesses two secA homologous genes that are essential for viability
Corynebacterium glutamicum possesses two secA homologous genes that are essential for viability
SecA is a central component of the bacterial Sec preprotein translocase. Besides the housekeeping SecA (SecA1), some mostly pathogenic Gram-positive bacteria possess an accessory SecA (SecA2) that is involved in the export of a few substrates only. Here we show that neither of the two secA homologou...
Saved in:
Personal Name(s): | Caspers, M. |
---|---|
Freudl, R. | |
Contributing Institute: |
Biotechnologie 1; IBT-1 |
Published in: | Archives of microbiology, 189 (2008) S. 605 - 610 |
Imprint: |
Berlin
Springer
2008
|
Physical Description: |
605 - 610 |
DOI: |
10.1007/s00203-008-0351-0 |
PubMed ID: |
18246326 |
Document Type: |
Journal Article |
Research Program: |
Biotechnologie |
Series Title: |
Archives of Microbiology
189 |
Subject (ZB): | |
Publikationsportal JuSER |
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100 | 1 | |a Caspers, M. |b 0 |u FZJ |0 P:(DE-Juel1)VDB13579 | |
245 | |a Corynebacterium glutamicum possesses two secA homologous genes that are essential for viability | ||
260 | |a Berlin |b Springer |c 2008 | ||
300 | |a 605 - 610 | ||
440 | 0 | |a Archives of Microbiology |x 0302-8933 |0 625 |v 189 | |
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520 | |a SecA is a central component of the bacterial Sec preprotein translocase. Besides the housekeeping SecA (SecA1), some mostly pathogenic Gram-positive bacteria possess an accessory SecA (SecA2) that is involved in the export of a few substrates only. Here we show that neither of the two secA homologous genes present in the genome of the non-pathogenic bacterium Corynebacterium glutamicum can be deleted, unless a copy of the respective gene is provided in trans on a plasmid. This finding is in marked contrast to all other cases examined so far making C. glutamicum the first reported bacterium possessing two essential SecA proteins. | ||
588 | |a Dataset connected to Web of Science, Pubmed | ||
650 | 2 | |2 MeSH |a Adenosine Triphosphatases: genetics | |
650 | 2 | |2 MeSH |a Adenosine Triphosphatases: metabolism | |
650 | 2 | |2 MeSH |a Bacterial Proteins: genetics | |
650 | 2 | |2 MeSH |a Bacterial Proteins: metabolism | |
650 | 2 | |2 MeSH |a Corynebacterium glutamicum: genetics | |
650 | 2 | |2 MeSH |a Corynebacterium glutamicum: growth & development | |
650 | 2 | |2 MeSH |a Corynebacterium glutamicum: metabolism | |
650 | 2 | |2 MeSH |a Gene Expression | |
650 | 2 | |2 MeSH |a Membrane Transport Proteins: genetics | |
650 | 2 | |2 MeSH |a Membrane Transport Proteins: metabolism | |
650 | 2 | |2 MeSH |a Microbial Viability | |
650 | 7 | |0 0 |2 NLM Chemicals |a Bacterial Proteins | |
650 | 7 | |0 0 |2 NLM Chemicals |a Membrane Transport Proteins | |
650 | 7 | |0 119129-39-4 |2 NLM Chemicals |a SecA protein, Bacteria | |
650 | 7 | |0 EC 3.6.1.- |2 NLM Chemicals |a Adenosine Triphosphatases | |
650 | 7 | |a J |2 WoSType | |
653 | 2 | 0 | |2 Author |a gram-positive bacteria |
653 | 2 | 0 | |2 Author |a corynebacterianeae |
653 | 2 | 0 | |2 Author |a protein secretion |
653 | 2 | 0 | |2 Author |a translocase subunit |
653 | 2 | 0 | |2 Author |a SecA |
700 | 1 | |a Freudl, R. |b 1 |u FZJ |0 P:(DE-Juel1)128960 | |
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