This title appears in the Scientific Report :
2016
Please use the identifier:
http://dx.doi.org/10.1116/1.4945306 in citations.
Please use the identifier: http://hdl.handle.net/2128/18155 in citations.
Positively charged supported lipid bilayer formation on gold surfaces for neuronal cell culture
Positively charged supported lipid bilayer formation on gold surfaces for neuronal cell culture
Supported lipid bilayers are widely used as cell membrane models and sensor platforms, but the usage on goldsurface needs additional surface modification or optimized experimental conditions. In this work, the authors show lipid bilayer formation on plasma activated goldsurfaces in physiological con...
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Personal Name(s): | Choi, Sung-Eun |
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Greben, Kyrylo / Wördenweber, Roger / Offenhäusser, Andreas (Corresponding author) | |
Contributing Institute: |
JARA-FIT; JARA-FIT Bioelektronik; ICS-8 Bioelektronik; PGI-8 |
Published in: | Biointerphases, 11 (2016) 2, S. 021003 - |
Imprint: |
Melville, NY
AIP
2016
|
DOI: |
10.1116/1.4945306 |
PubMed ID: |
27052005 |
Document Type: |
Journal Article |
Research Program: |
Engineering Cell Function |
Link: |
OpenAccess OpenAccess |
Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/18155 in citations.
Supported lipid bilayers are widely used as cell membrane models and sensor platforms, but the usage on goldsurface needs additional surface modification or optimized experimental conditions. In this work, the authors show lipid bilayer formation on plasma activated goldsurfaces in physiological conditions without any other modification if at least 30% positively charged lipids are present. Details of bilayer formation from small unilamellar vesicles were monitored using quartz crystal microbalance with dissipation in both basic and acidic environment. The authors also confirmed that this positively charged bilayer system can sustain primary cortical neuron growth and lipid transfer. This method will provide simple means to construct biomimetic interface on gold electrodes. |