This title appears in the Scientific Report :
2017
Please use the identifier:
http://dx.doi.org/10.1134/S1027451016050499 in citations.
Structure and phase transitions of DMPC multilamellar vesicles in the presence of Ca2+ ions
Structure and phase transitions of DMPC multilamellar vesicles in the presence of Ca2+ ions
Results obtained via small-angle neutron scattering studies of the influence of calcium ions on the structure and phase transitions of phospholipid membranes are presented. The main phase transition temperature of 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (1 wt %) multilamellar vesicles is de...
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Personal Name(s): | Gorshkova, Yu. E. (Corresponding author) |
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Kuklin, A. I. / Gordeliy, Valentin | |
Contributing Institute: |
Strukturbiochemie; ICS-6 |
Published in: | Journal of surface investigation, 11 (2017) 1, S. 27–37 |
Imprint: |
Moscow
MAIK Nauka/Interperiodics Publ.
2017
|
DOI: |
10.1134/S1027451016050499 |
Document Type: |
Journal Article |
Research Program: |
Functional Macromolecules and Complexes |
Publikationsportal JuSER |
Results obtained via small-angle neutron scattering studies of the influence of calcium ions on the structure and phase transitions of phospholipid membranes are presented. The main phase transition temperature of 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (1 wt %) multilamellar vesicles is demonstrated to increase by more than 1°C even when the calcium-ion content of the solution is low (0.1 mM). Detailed analysis of the multilamellar vesicles transition between “bound” and “unbound” state indicates the continuous character of the investigated process in both liquid and gel phases. The critical Ca2+ ion concentrations which initiate the destruction of the multilamellar structures and the formation of unilamellar vesicles are found to be ~0.3 mM in the gel and ~0.4–0.5 mM in the liquid-crystal phases during heating and ~0.5 mM in the phases under study upon cooling. |