This title appears in the Scientific Report :
2017
Please use the identifier:
http://dx.doi.org/10.1007/s12268-017-0850-0 in citations.
Optische Genregulation in Mikrobioreaktoren
Optische Genregulation in Mikrobioreaktoren
Photolabile-caged effector molecules allow non-invasive regulation of gene expression using cell-compatible UVA-irradiation. Based on this method, independent photoregulation of gene expression was combined with optical online monitoring of important cultivation parameters in a 48-well plate format....
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Personal Name(s): | Kusen, Peter M. (Corresponding author) |
---|---|
Hoffmann, Kyra / Wandrey, Georg / Büchs, Jochen / Pietruszka, Jörg | |
Contributing Institute: |
Institut für Bioorganische Chemie (HHUD); IBOC Biotechnologie; IBG-1 |
Published in: | Biospektrum, 23 (2017) 6, S. 643-645 |
Imprint: |
Heidelberg
Spektrum
2017
|
DOI: |
10.1007/s12268-017-0850-0 |
Document Type: |
Journal Article |
Research Program: |
Biotechnology |
Publikationsportal JuSER |
Photolabile-caged effector molecules allow non-invasive regulation of gene expression using cell-compatible UVA-irradiation. Based on this method, independent photoregulation of gene expression was combined with optical online monitoring of important cultivation parameters in a 48-well plate format. Thereby, an innovative screening system was created which allows for cost-effective and easily automated expression profiling as well as closed-loop process control. |