This title appears in the Scientific Report :
2018
Please use the identifier:
http://dx.doi.org/10.1186/s40694-018-0053-6 in citations.
Please use the identifier: http://hdl.handle.net/2128/18424 in citations.
Improved microscale cultivation of Pichia pastoris for clonal screening
Improved microscale cultivation of Pichia pastoris for clonal screening
Expanding the application of technical enzymes, e.g., in industry and agriculture, commands the acceleration and cost-reduction of bioprocess development. Microplates and shake flasks are massively employed during screenings and early phases of bioprocess development, although major drawbacks such a...
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Personal Name(s): | Eck, Alexander |
---|---|
Schmidt, Matthias / Hamer, Stefanie / Ruff, Anna Joelle / Förster, Jan / Schwaneberg, Ulrich / Blank, Lars M. / Wiechert, Wolfgang / Oldiges, Marco (Corresponding author) | |
Contributing Institute: |
Biotechnologie; IBG-1 |
Published in: | Fungal Biology and Biotechnology, 5 (2018) 1, S. 8 |
Imprint: |
London
BioMed Central
2018
|
PubMed ID: |
29750118 |
DOI: |
10.1186/s40694-018-0053-6 |
Document Type: |
Journal Article |
Research Program: |
Biotechnology |
Link: |
OpenAccess OpenAccess |
Publikationsportal JuSER |
Please use the identifier: http://hdl.handle.net/2128/18424 in citations.
Expanding the application of technical enzymes, e.g., in industry and agriculture, commands the acceleration and cost-reduction of bioprocess development. Microplates and shake flasks are massively employed during screenings and early phases of bioprocess development, although major drawbacks such as low oxygen transfer rates are well documented. In recent years, miniaturization and parallelization of stirred and shaken bioreactor concepts have led to the development of novel microbioreactor concepts. They combine high cultivation throughput with reproducibility and scalability, and represent promising tools for bioprocess development. ... |