This title appears in the Scientific Report :
2020
Please use the identifier:
http://hdl.handle.net/2128/24497 in citations.
Please use the identifier: http://dx.doi.org/10.1093/neuonc/noz236 in citations.
Combined FET PET/ADC mapping: improved imaging of glioma infiltration?
Combined FET PET/ADC mapping: improved imaging of glioma infiltration?
Conventional MRI is the method of choice for the diagnosis of cerebral gliomas owing to its ability to detect structural changes with high spatial resolution and outstanding sensitivity. In malignant gliomas, the determination of tumor extent is primarily based on the assessment of blood–brain barri...
| Personal Name(s): | Langen, Karl-Josef (Corresponding author) |
|---|---|
| Galldiks, Norbert / Lohmann, Philipp | |
| Contributing Institute: |
Physik der Medizinischen Bildgebung; INM-4 Kognitive Neurowissenschaften; INM-3 |
| Published in: | Neuro-Oncology, 22 (2020) 3, S. 313-314 |
| Imprint: |
Oxford
Oxford Univ. Press
2020
|
| PubMed ID: |
31859354 |
| DOI: |
10.1093/neuonc/noz236 |
| Document Type: |
Journal Article |
| Research Program: |
(Dys-)function and Plasticity |
| Link: |
Published on 2019-12-20. Available in OpenAccess from 2020-12-20. Restricted Published on 2019-12-20. Available in OpenAccess from 2020-12-20. Restricted |
| Publikationsportal JuSER |
Please use the identifier: http://dx.doi.org/10.1093/neuonc/noz236 in citations.
|
Conventional MRI is the method of choice for the diagnosis of cerebral gliomas owing to its ability to detect structural changes with high spatial resolution and outstanding sensitivity. In malignant gliomas, the determination of tumor extent is primarily based on the assessment of blood–brain barrier (BBB) disruption as reflected by contrast enhancement after application of paramagnetic contrast media. In gliomas of World Health Organization (WHO) grades II and III, which are frequently non-enhancing, estimation of tumor extent relies on signal abnormalities in T2-weighted MRI or in the fluid-attenuated inversion recovery (FLAIR) sequence. It is well known, however, that neither contrast enhancement nor FLAIR abnormalities are specific for neoplastic tissue.... |