This title appears in the Scientific Report :
2022
Please use the identifier:
http://hdl.handle.net/2128/31547 in citations.
Role of secondary metabolites in antiphage defense in Streptomyces
Role of secondary metabolites in antiphage defense in Streptomyces
Bacteriophages (phages) are viruses preying on bacteria and as such pose a major and ubiquitousthreat to bacterial communities. To cope with viral challenges, bacteria have evolved a diversifiedarsenal of defense systems. However, this repertoire is known to rely predominantly on protein orRNA effec...
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Personal Name(s): | Hardy, Aël (Corresponding author) |
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Contributing Institute: |
Biotechnologie; IBG-1 |
Imprint: |
Jülich
Forschungszentrum Jülich GmbH Zentralbibliothek, Verlag
2022
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Physical Description: |
208 |
Dissertation Note: |
Dissertation, HHU Duesseldorf, 2022 |
ISBN: |
978-3-95806-633-5 |
Document Type: |
Book Dissertation / PhD Thesis |
Research Program: |
Biological and environmental resources for sustainable use |
Series Title: |
Schriften des Forschungszentrums Jülich Reihe Schlüsseltechnologien / Key Technologies
254 |
Link: |
OpenAccess |
Publikationsportal JuSER |
Bacteriophages (phages) are viruses preying on bacteria and as such pose a major and ubiquitousthreat to bacterial communities. To cope with viral challenges, bacteria have evolved a diversifiedarsenal of defense systems. However, this repertoire is known to rely predominantly on protein orRNA effectors. On the other hand, bacteria produce an extraordinary diversity of secondarymetabolites, whose physiological function is often unknown. In this thesis, we explore the role ofbacterial secondary metabolites in the defense against phage predation. To this end, we used as amodel system Streptomyces, a prolific producer of secondary metabolites |