David Holcman

David Holcman is an applied mathematician, biophysicist and computational biologist at École Normale Supérieure in Paris. He is known for his work on the narrow escape problem, the redundancy principle in biology, the modeling of molecular trafficking in neurobiology, of diffusion and electrodiffusion in dendritic spines, the modeling of neuronal network dynamics such as Up and Down states in electrophysiology. He developed multiscale methods to analyse large amount of molecular super-resolution trajectories, and polymer physics modeling and analysis to study cell nucleus organization. These approaches led to several verified predictions in the life sciences such as nanocolumn organization of synapses or astrocytic protrusion penetrating neuronal synapses. Provided by Wikipedia