Computational Toxicology [E-Book]: Volume I / edited by Brad Reisfeld, Arthur N. Mayeno.
Rapid advances in computer science, biology, chemistry, and other disciplines are enabling powerful new computational tools and models for toxicology and pharmacology. These computational tools hold tremendous promise for advancing science, from streamlining drug efficacy and safety testing, to incr...
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Full text |
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Personal Name(s): | Mayeno, Arthur N. |
Reisfeld, Brad. | |
Imprint: |
Totowa, NJ :
Humana Press,
2013
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Physical Description: |
XI, 613 p. 157 illus., 75 illus. in color. digital. |
Note: |
englisch |
ISBN: |
9781627030502 |
DOI: |
10.1007/978-1-62703-050-2 |
Series Title: |
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Methods in molecular biology, methods and protocols ;
929 |
Subject (ZB): | |
Subject (LOC): |
- What is Computational Toxicology?
- Computational Toxicology – Application in Environmental Chemicals
- Role of Computational Methods in Pharmaceutical Sciences
- Best Practices in Mathematical Modeling
- Tools and Techniques
- Prediction of Physicochemical Properties
- Informing Mechanistic Toxicology with Computational Molecular Models
- Chemical Structure Representations and Applications in Computational Toxicity
- Accessing and Using Chemical Property Databases
- Accessing, Using and Creating Chemical Property Databases for Computational Toxicology Modeling
- Molecular Dynamics
- Introduction to Pharmacokinetics in Clinical Toxicology.-Modeling of Absorption
- Prediction of Pharmacokinetic Parameters
- Ligand – And Structure-Based Pregnane X Receptor Models
- Non-Compartmental Analysis
- Compartmental Modeling in the Analysis of Biological Systems
- Physicologically Based Pharmacokinetic/Toxicokinetic Modeling
- Interspecies Extrapolation
- Population Effects and Variability
- Mechanism-Based Pharmacodynamic Modeling..