Pharmacogenomics [E-Book] : Methods and Protocols / edited by Federico Innocenti, Ron H.N. Schaik.
Understanding an individual's genetic makeup is the key to creating personalized drugs with greater efficacy and safety, and pharmacogenomics aims to study the complex genetic basis of inter-patient variability in response to drug therapy. Based upon the success of its first edition, the secon...
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Full text |
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Personal Name(s): | Innocenti, Federico. editor |
Schaik, Ron H.N. editor | |
Edition: |
2nd ed. 2013. |
Imprint: |
Totowa, NJ :
Humana Press,
2013
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Physical Description: |
XIII, 359 p. 56 illus., 33 illus. in color. online resource. |
Note: |
englisch |
ISBN: |
9781627034357 |
DOI: |
10.1007/978-1-62703-435-7 |
Series Title: |
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Methods in molecular biology, methods and protocols ;
1015 |
Subject (ZB): | |
Classification: |
- Pharmacogenomics: Historical Perspective and Current Status
- Denaturing High-Performance Liquid Chromatography for Mutation Detection and Genotyping
- Clinical SNP Detection by the SmartAmp Method
- MALDI-TOF Mass Spectrometry
- TaqMan® Drug Metabolism Genotyping Assays for the Detection of Human Polymorphisms Involved in Drug Metabolism
- Pyrosequencing of Clinically Relevant Polymorphisms
- Pharmacogenetics Using Luminex® xMAP® Technology: Method for Developing a Custom Multiplex Single Nucleotide Polymorphism Mutation Assay
- Use of Linkage Analysis, Genome-Wide Association Studies, and Next-Generation Sequencing in the Identification of Disease-Causing Mutations
- The GoldenGate Genotyping Assay: Custom Design, Processing, and Data Analysis
- Genome-Wide Gene Expression Profiling, Genotyping, and Copy Number Analyses of Acute Myeloid Leukemia Using Affymetrix GeneChips
- Epigenetic Techniques in Pharmacogenetics
- Plasmid Derived External Quality Controls for Genetic Testing
- Allelic Imbalance Assays to Quantify Allele-Specific Gene Expression and Transcription Factor Binding
- SCAN: A Systems Biology Approach to Pharmacogenomic Discovery
- Methods to Examine the Impact of Nonsynonymous SNPs on Protein Degradation and Function of Human ABC Transporter
- In Vitro Identification of Cytochrome P450 Enzymes Responsible for Drug Metabolism
- In Vitro and In Vivo Mouse Models for Pharmacogenetic Studies
- The Hydrodynamic Tail Vein Assay as a Tool for the Study of Liver Promoters and Enhancers
- A Guide to the Current Web-Based Resources in Pharmacogenomics
- PharmGKB: The Pharmacogenomics Knowledge Base
- Genetic Databases in Pharmacogenomics: The Frequency of Inherited Disorders Database (FINDbase)
- Development of Predictive Models for Estimating Warfarin Maintenance Dose Based on Genetic and Clinical Factors
- Evidence Based Drug Dosing and Pharmacotherapeutic Recommendations Per Genotype.