LC-MS in Drug Bioanalysis [E-Book] / edited by Q. Alan Xu, Timothy L. Madden.
High performance liquid chromatography – mass spectrometry (LC-MS) combines the separation power of liquid chromatography with the high sensitivity and selectivity of mass spectrometry. Therefore, LC-MS becomes the method of choice for drug bioanalysis in therapeutic drug monitoring, tox...
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Full text |
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Personal Name(s): | Xu, Q. Alan. editor |
Madden, Timothy L. editor | |
Imprint: |
Boston, MA :
Springer,
2012
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Physical Description: |
XI, 469 p. 118 illus., 30 illus. in color. online resource. |
Note: |
englisch |
ISBN: |
9781461438281 |
DOI: |
10.1007/978-1-4614-3828-1 |
Subject (LOC): |
- Internal standards for quantitative LC-MS bioanalysis
- Method development, validation and sample analysis for regulated quantitative bioanalysis using LC-MS/MS
- Impact of sampling paper/cards on bioanalytical quantitation via dried blood spots by liquid chromatography - mass spectrometry
- Highly sensitive pharmaceutical and clinical analysis using selective solid-phase extraction coupled to microflow liquid chromatography and isotope-dilution mass spectrometry
- Pitfalls of LC-MS/MS in the clinical laboratory
- Therapeutic drug monitoring to support clinical pharmacogenomics
- Liquid chromatography - mass spectrometry for the determination of antidepressants and some of their major metabolites in human biological matrices
- The analysis of antipsychotic drugs in human biosamples by LC-MS
- Therapeutic drug monitoring of targeted anticancer therapy - tyrosine kinase inhibitors and selective oestrogen receptor modulators: a clinical pharmacology laboratory perspective
- Applications of mass spectrometry in analyses of steroid hormones
- Liquid chromatography - mass spectrometric analysis of tropane alkaloids in mammalian samples: techniques and applications
- Analysis of illicit drugs in human biological samples by LC-MSn
- Use of matrix assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) in the development of novel small molecule drugs
- A planar integrated micro mass spectrometer.