Alternatives to animal testing / editors, R.E. Hester and R.M. Harrison [E-Book]
This product is not available separately, it is only sold as part of a set. There are 750 products in the set and these are all sold as one entity.
Saved in:
Full text |
|
Personal Name(s): | Hester, R. E. |
Harrison, Roy M., | |
Imprint: |
Cambridge, UK :
Royal Society of Chemistry,
c2006
|
Physical Description: |
1 online resource |
Note: |
englisch |
ISBN: |
1847552455 9781847552457 |
DOI: |
10.1039/9781847552457 |
Series Title: |
/* Depending on the record driver, $field may either be an array with
"name" and "number" keys or a flat string containing only the series
name. We should account for both cases to maximize compatibility. */?>
Issues in environmental science and technology ;
23 |
Subject (LOC): |
- GENERAL OVERVIEW OF THE SAFETY EVALUATION OF CHEMICALS / Paul Illing
- Introduction
- Legislation and regulatory requirements
- The regulatory paradigm
- The interface between toxicology and risk assessment
- Interpreting toxicology
- Conclusions
- References
- INTERNATIONAL VALIDATION AND BARRIERS TO THE VALIDATION OF ALTERNATIVE TESTS / Michael Balls
- Introduction
- Background to the validation process
- The validation process
- Problems being encountered in implementing the validation process
- The need for an invalidation process
- Concluding remarks
- References
- IN VITRO TESTING FOR ENDOCRINE DISRUPTORS / Robert D. Combes
- Introduction
- In silico approaches
- In vitro tests for EDs
- Discussion
- Conclusions
- Acknowledgment
- References
- iNTELLIGENT APPROACHES TO SAFETY EVALUATION / Derek J. Knight
- Introduction
- Hazardous properties assessment
- Risk assessment
- Existing studies and literature data
- Surrogate data: calculation, read across and SAR/QSAR
- Alternatives to animal toxicology studies
- Data waivers
- Expert reports and weight of evidence
- Preliminary risk assessments
- EU Registration, Evaluation and Registration Scheme (REACH)
- Data for REACH
- Regulatory planning & liaison with the regulators
- Common themes
- Acknowledgments
- References
- ALTERNATIVE TESTS AND THE 7TH AMENDMENT TO THE COSMETICS DIRECTIVE / Carl Westmoreland
- Introduction
- Overview of current approaches to risk assessment for cosmetics
- 7th Amendment to the EU Cosmetics Directive (76/768/EEC)
- Status of alternative tests
- Endpoints where risk assessment for cosmetics can be achieved without using animal data
- Endpoints where risk assessment for cosmetics cannot currently be achieved without using animal data
- New approaches to risk assessment without animals
- Acknowledgments
- Abbreviations
- References.