Nucleic Acid Structure [E-Book] : An Introduction / by Wilhelm Guschlbauer.
Teaching a course on nucleic acid structure is a hazardous undertaking, especially if one has no continuous teaching obligations. I still have done it on several occasions in various French universities, when colleagues, suffering from admin istrative overwork and excessive teaching obligations, ha...
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Full text |
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Personal Name(s): | Guschlbauer, Wilhelm, author |
Imprint: |
New York, NY :
Springer New York,
1976
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Physical Description: |
XII, 146 p. 11 illus. online resource. |
Note: |
englisch |
ISBN: |
9781461393979 |
DOI: |
10.1007/978-1-4613-9397-9 |
Series Title: |
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Heidelberg Science Library
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Subject (LOC): |
- 1 Introduction
- 1.1 History
- 1.2 Cellular localization of nucleic acids
- 2 Methods and Techniques
- 2.1 Absorption and optical activity (ORD and CD)
- 2.2 Nuclear magnetic resonance (NMR)
- 2.3 Ultracentrifugation
- 2.4 X-ray fiber diffraction
- 3 Chemistry and Enzymology of Nucleic Acids
- 3.1 Chemistry of nucleic acids and their constituents
- 3.2 Chemical reactions of nucleic acids and their constituents
- 3.3 Isolation of nucleic acids
- 3.4 Degradation and determination of nucleic acids
- 4 Structure and Function of DNA
- 4.1 The double helix of Watson and Crick
- 4.2 Experimental tests of the Watson-Crick hypothesis
- 4.3 The role of DNA in the cellular machinery—the central dogma
- 5 Physical Chemistry of DNA—The Problems of DNA Research
- 5.1 Established facts
- 5.2 Facts that may require amendments of details of the Watson–Crick theory
- 5.3 What do we require from biologically operative DNA?
- 5.4 What do we still not know?
- 6 Model Systems for Nucleic Acids
- 6.1 Polynucleotides
- 6.2 Oligonucleotides
- 6.3 Association of monomers in solutions and crystals
- 7 Errors and Mutations
- 7.1 Chemical mutagenesis
- 7.2 Base analogues
- 7.3 Antibiotics, pigments, dyes
- 7.4 Mutagenesis by radiation (UV, X-rays)
- 8 The Structure of Ribonucleic Acids
- 8.1 Protein biosynthesis
- 8.2 Transfer RNA
- 8.3 Ribosome structure and rRNA
- 8.4 Viral RNA and virus structure
- 9 Nucleic Acid—Protein Interactions
- 9.1 Polyamines
- 9.2 Polypeptides and protamines
- 9.3 Histones and chromatin
- In the Guise of an Epilogue
- Appendix: Abbreviations and Symbols for Nucleic Acids, Polynucleotides, and Their Constituents
- Suggested Bibliography for Advanced Reading.