Bioorganic Chemistry [E-Book] : A Chemical Approach to Enzyme Action / by Hermann Dugas.
Springer Advanced Texts In Chemistry New textbooks at all levels of chemistry appear with great regularity. Some fields like basic biochemistry, organic reaction mechanisms, and chemical thermody namics are well represented by many excellent texts, and new or revised editions are published sufficie...
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Full text |
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Personal Name(s): | Dugas, Hermann, author |
Edition: |
Second Edition. |
Imprint: |
New York, NY :
Springer,
1989
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Physical Description: |
XV, 651 p. online resource. |
Note: |
englisch |
ISBN: |
9781468403244 |
DOI: |
10.1007/978-1-4684-0324-4 |
Series Title: |
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Springer Advanced Texts in Chemistry
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Subject (LOC): |
- 1 Introduction to Bioorganic Chemistry
- 1.1 1 Basic Considerations
- 1.2 Proximity Effects in Organic Chemistry
- 1.3 Molecular Adaptation
- 1.4 Molecular Recognition and the Supramolecular Level
- 2 Bioorganic Chemistry of Amino Acids and Polypeptides
- 2.1 Chemistry of the Living Cells
- 2.2 Analogy Between Organic Reactions and Biochemical Transformations
- 2.3 Chemistry of the Peptide Bond
- 2.4 Nonribosomal Peptide Bond Formation
- 2.5 Asymmetric Synthesis of a-Amino Acids
- 2.6 Asymmetric Synthesis with Chiral Organometallic Catalysts
- 2.7 Transition State Analogs
- 2.8 Antibodies as Enzymes
- 2.9 Chemical Mutations
- 2.10 Molecular Recognition and Drug Design
- 3 Bioorganic Chemistry of the Phosphate Groups and Polynucleotides
- 3.1 Basic Considerations
- 3.2 Energy Storage
- 3.3 Hydrolytic Pathways and Pseudorotation
- 3.4 DNA Intercalants
- 3.5 Chemical Evolution of Biopolymers
- 3.6 RNA Molecules as Catalysts
- 4 Enzyme Chemistry
- 4.1 Introduction to Catalysis
- 4.2 Introduction to Enzymes
- 4.3 Multifunctional Catalysis and Simple Models
- 4.4 a-Chymotrypsin
- 4.5 Other Hydrolytic Enzymes
- 4.6 Stereoelectronic Control in Hydrolytic Reactions
- 4.7 Immobilized Enzymes and Enzyme Technology
- 4.8 Enzymes in Synthetic Organic Chemistry
- 4.9 Enzyme-Analog-Built Polymers
- 4.10 Design of Molecular Clefts
- 5 Enzyme Models
- 5.1 Host-Guest Complexation Chemistry
- 5.2 New Developments in Crown Ether Chemistry
- 5.3 Membrane Chemistry and Micelles
- 5.4 Polymers
- 5.5 Cyclodextrins
- 5.6 Enzyme Design Using Steroid Template
- 5.7 Remote Functionalization Reactions
- 5.8 Biomimetic Polyene Cyclizations
- 6 Metal Ions
- 6.1 Metal Ions in Proteins and Biological Molecules
- 6.2 Carboxypeptidase A and the Role of Zinc
- 6.3 Hydrolysis of Amino Acid Esters and Amides and Peptides
- 6.4 Iron and Oxygen Transport
- 6.5 Copper Ion
- 6.6 Biomodels of Photosynthesis and Energy Transfer
- 6.7 Cobalt and Vitamin B12 Action
- 7 Coenzyme Chemistry
- 7.1 Oxidoreduction
- 7.2 Pyridoxal Phosphate
- 7.3 Suicide Enzyme Inactivators and Affinity Labels
- 7.4 Thiamine Pyrophosphate
- 7.5 Biotin
- References.