NMR in glycoscience and glycotechnology [E-Book] / editors: Koichi Kato, Thomas Peters.
This volume focuses on solution and solid-state NMR of carbohydrates, glycoproteins, glyco-technologies, biomass and related topics. Timely and useful, it will appeal to researchers in the general field of structural biology, biochemistry and biophysics, molecular and cellular biology and material s...
Saved in:
Full text |
|
Personal Name(s): | Kato, Koichi, editor |
Peters, Thomas, editor | |
Imprint: |
[Cambridge] :
Royal Society of Chemistry,
2017
|
Physical Description: |
1 online resource : color illustrations. |
Note: |
englisch |
ISBN: |
9781782623946 1782623949 |
Series Title: |
/* Depending on the record driver, $field may either be an array with
"name" and "number" keys or a flat string containing only the series
name. We should account for both cases to maximize compatibility. */?>
New developments in NMR ;
10 |
Subject (ZB): | |
Subject (LOC): | |
Classification: |
- Cover; NMR in Glycoscience and Glycotechnology; Preface; Contents; Chapter 1
- Intramolecular Hydrogen Bonding in Glycans in Aqueous Solution; 1.1 Introduction; 1.2 NH Hydrogen Bonding; 1.3 OH Detection and Hydrogen Bonding; 1.3.1 Measuring OH Exchange Rate Constants for Inferring Hydrogen Bonding; 1.4 Hydrogen Bonding Involving C-H Bonds as Donors; 1.5 Hydrogen Bonding Between OH and Carboxylate Groups; 1.6 Future Directions; References; Chapter 2
- NMR Spin-Couplings in Saccharides: Relationships Between Structure, Conformation and the Magnitudes of JHH, JCH and JCC Values
- 2.1 Introduction and Background2.2 Empirical Predictions of 2JCH and 2JCC Values in Saccharides; 2.3 Experimental Determinations of Spin-Coupling Signs in Saccharides; 2.4 Second-Order Behavior in 1H and 13C NMR Spectra of Saccharides; 2.5 Structural Elements of Saccharides and Factors that Influence Them; 2.5.1 Ring Conformation; 2.5.2 Exocyclic Hydroxymethyl Conformation; 2.5.3 Exocyclic C-O Bond Conformation; 2.5.4 Exocyclic N-Acetyl Group Conformation; 2.5.5 O-Glycosidic Linkage Conformation; 2.6 Assets and Limitations of J-Couplings to Determine Saccharide Structure
- 2.7 Core Relationships Between J-Coupling and Saccharide Structure2.7.1 High Abundance of Oxygen and Nitrogen Lone-Pair Orbitals in Saccharides; 2.7.2 Two-Bond (Geminal) 13C-1H and 13C-13C Spin-Couplings; 2.7.3 Three-Bond (Vicinal) 13C-1H and 13C-13C Spin-Couplings; 2.7.4 Dual-Pathway 13C-13C Spin-Couplings in Aldopyranosyl and Aldofuranosyl Rings; 2.7.5 Four-Bond 1H-1H and 13C-1H Spin-Couplings in Aldopyranosyl Rings; 2.7.6 Spin-Couplings Across O-Glycosidic Linkages in Oligosaccharides; 2.8 Measurement of NMR Spin-Couplings in Solids; 2.9 Concluding Remarks; Acknowledgements; References
- 3.3.6 Strategies to Obtain Good Intermolecular NOEs for High Affinity Complexes3.3.7 Low Affinity
- A Problem for Protein-Carbohydrate Structure Determination; 3.3.8 Influence of the Field Strength and Other Parameters on Intermolecular NOEs; 3.3.9 Other Complications and Solutions; 3.3.10 Promising Technological Developments Applicable to Protein-Carbohydrate Complexes; 3.4 Judging the Quality of Protein-Carbohydrate Complex Structures Determined by NMR; 3.5 Conclusions; Acknowledgements; References; Chapter 4
- Paramagnetic, RDC and RCSA Constraints in the Structural Analysis of Glycans
- Chapter 3
- Insights into Carbohydrate Recognition by 3D Structure Determination of Protein-Carbohydrate Complexes Using NMR3.1 Introduction; 3.2 Overview of Protein-Carbohydrate Structures Determined by NMR; 3.3 Three-Dimensional Structure Determination by NMR Spectroscopy; 3.3.1 The Importance of Intermolecular NOEs; 3.3.2 NMR Pulse Sequences to Detect Intermolecular NOEs; 3.3.3 Isotope Labelling of Oligosaccharides; 3.3.4 Line Broadening at the Recognition Interface; 3.3.5 Binding Equilibria and Their Consequences on Detecting Intermolecular NOEs