Immuno-Oncology [E-Book] : Cellular and Translational Approaches / edited by Seng-Lai Tan.
Tan, Seng-Lai, (editor)
1st edition 2020.
New York, NY : Humana Press, 2020
X, 262 pages 91 illustrations, 83 illustrations in color (online resource)
Methods in Pharmacology and Toxicology
Full Text
Table of Contents:
  • An In Vitro System Combining Tumor Cells and Lymphocytes to Predict the In Vivo Response of Immunomodulatory Antibodies
  • High-Throughput Direct Cell Counting Method for Immuno-Oncology Functional Assays Using Image Cytometry
  • In Vitro Immunotherapy Potency Assays Using Real-Time Cell Analysis
  • Assessing the Potency of T Cell-Redirecting Therapeutics Using In Vitro Cancer Cell Killing Assays
  • Induction and Potential Reversal of a T Cell Exhaustion-Like State: In Vitro Potency Assay for Functional Screening of Immune Checkpoint Drug Candidates
  • Validation of an Image-Based 3D Natural Killer Cell-Mediated Cytotoxicity Assay
  • 3D-3-Culture: Tumor Models to Study Heterotypic Interactions in the Tumor Microenvironment
  • Considerations in Developing Reporter Gene Bioassays for Biologics
  • Miniaturized Single Cell Imaging for Developing Immuno-Oncology Combinational Therapies
  • Precision Medicine: The Function of Receptor Occupancy in Drug Development
  • In Vitro Assays for Assessing Potential Adverse Effects of Cancer Immunotherapeutics
  • The Quest for the Next-Generation of Tumor Targets: Discovery and Prioritization in the Genomics Era.