Experimental Models of Parkinson's Disease [E-Book] / edited by Yuzuru Imai.
This detailed book focuses on cutting-edge methods for Parkinson's disease (PD) research, such as the analysis of the prion-like properties of -synuclein, mitochondrial functions related to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway related to LRRK2, VPS35, and ATP13A2 using cult...
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Full text |
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Personal Name(s): | Imai, Yuzuru, editor |
Edition: |
1st edition 2021. |
Imprint: |
New York, NY :
Humana Press,
2021
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Physical Description: |
XI, 217 pages 57 illustrations, 47 illustrations in color (online resource) |
Note: |
englisch |
ISBN: |
9781071614952 |
DOI: |
10.1007/978-1-0716-1495-2 |
Series Title: |
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Methods in Molecular Biology ;
2322 |
Subject (ZB): | |
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- -Synuclein Seeding Assay Using RT-QuIC
- Electron-Microscopic Analysis of -Synuclein Fibrils
- -Synuclein Seeding Assay Using Cultured Cells
- Analysis of -Synuclein in Exosomes
- Measurement of GCase Activity in Cultured Cells
- Detection of Substrate Phosphorylation of LRRK2 in Tissues and Cultured Cells
- Two Methods to Analyze LRRK2 Functions Under Lysosomal Stress: The Measurements of Cathepsin Release and Lysosomal Enlargement
- Differentiation of Midbrain Dopaminergic Neurons from Human iPS Cells
- Monitoring PINK1-Parkin Signaling Using Dopaminergic Neurons from iPS Cells
- Generation of Mitochondrial Toxin Rodent Models of Parkinson's Disease Using 6-OHDA, MPTP, and Rotenone
- Midbrain Slice Culture as an Ex Vivo Analysis Platform for Parkinson's Disease
- -Synuclein Propagation Mouse Models of Parkinson's Disease
- Common Marmoset Model of -Synuclein Propagation
- Application of a Tissue Clearing Method for the Analysis of Dopaminergic Axonal Projections
- Deep Brain Stimulation Using Animal Models of Parkinson's Disease
- Assessment of Cytotoxicity of -Synuclein in Budding Yeast Using a Spot Growth Assay and Fluorescent Microscopy
- The Functional Assessment of LRRK2 in Caenorhabditis elegans Mechanosensory Neurons
- Analysis of Dopaminergic Functions in Drosophila
- Evaluation of Mitochondrial Function and Morphology in Drosophila
- Cytosolic and Mitochondrial Ca2+ Imaging in Drosophila Dopaminergic Neurons.