Tuning Autophagy-Inducing Activity and Toxicity for Lanthanide Nanocrystals [E-Book] / by Yunjiao Zhang.
This thesis presents a simple, yet highly effective surface engineering solution that uses non-covalent binding peptides to control the autophagy-inducing activity of nanomaterials and nanodevices. The author presents RE-1, a short synthetic peptide that sequence-specifically binds to lanthanide (LN...
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Full text |
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Personal Name(s): | Zhang, Yunjiao, author |
Edition: |
1st edition 2022. |
Imprint: |
Singapore :
Springer,
2022
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Physical Description: |
XV, 156 pages 78 illustrations, 66 illustrations in color (online resource) |
Note: |
englisch |
ISBN: |
9789811681660 |
DOI: |
10.1007/978-981-16-8166-0 |
Series Title: |
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Springer Theses, Recognizing Outstanding Ph.D. Research
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Subject (LOC): |
- Introduction
- Phage display identifies a specific high-affinity binding peptide RE-1 for lanthanide (LN) nanomaterials
- RE-1 forms a stable coating layer on the surface of upconversion nanoparticles / nanocrystals (UCN)
- Reduction of UCN sedimentation and nanomaterial-cell interaction by RE-1 coating
- RE-1 coating abrogates autophagy induction and toxicity for UCN in vitro and in vivo
- Enhancement of cell interaction and autophagy induction by coating with RE-1-RGD.-Conclusion and prospect.