Biomarkers for Huntington's Disease [E-Book] : Improving Clinical Outcomes / edited by Elizabeth A. Thomas, Georgia M. Parkin.
Huntington's disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations and cognitive decline. Early genetic testing provides an opportunity for clinical interventions aimed at delaying onset and/or slowing progressio...
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Full text |
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Personal Name(s): | Parkin, Georgia M., editor |
Thomas, Elizabeth A., editor | |
Edition: |
1st edition 2023. |
Imprint: |
Cham :
Springer,
2023
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Physical Description: |
XVI, 475 pages 42 illustrations, 39 illustrations in color (online resource) |
Note: |
englisch |
ISBN: |
9783031328152 |
DOI: |
10.1007/978-3-031-32815-2 |
Series Title: |
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Contemporary Clinical Neuroscience
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Subject (LOC): |
- Molecular Biomarkers.Somatic instability/Telomeres,- Genetic modifiers
- Current clinical trial biomarkers.-Pharmacodynamic biomarkers for Htt-lowering therapeutics.-Inflammatory biomarkers.-Sleep dysregulation markers.-Mitochondrial/Oxidative stress biomarkers.-Microbiomics
- Metabolomics.-Proteomics.-Transcriptomics.-Lipidomics.-Imaging marker overview.-Retinal imaging biomarkers
- MRI - non-invasive functional MRI measures
- The evolution of clinical trial methodology.-Digital biomarkers
- The future of telehealth
- Summary and future trends.